Human hGH ELISA Kit
from
Diagnostic Systems Laboratories, Inc.
|
|
|
|
Product
|
Human hGH ELISA Kit
|
|
Company
|
Diagnostic Systems Laboratories, Inc.
|
|
Price
|
|
|
More Information
|
View Company Product Page
|
|
Method
|
ELISA
|
|
Original Item Name
|
hGH ELISA Test
|
|
Regulatory Status
|
For In Vitro Diagnostic Use
|
|
Sample Type
|
Serum
|
|
Species
|
Human
|
|
Target
|
hGH
|
|
Target/Molecule Synonym
|
Human hGH
|
|
Time
|
Incubation Time: 1 hr + 30 mins + 10 mins on shaker at RT
|
|
Volume
|
20 µL
|
|
Detection
|
Request Info
|
|
Catalog Number
|
DSL-10-1900
|
|
Quantity
|
96 wells
|
|
Sensitivity
|
0.03 ng/mL
|
|
Range
|
7, 0.2 - 30 ng/mL
|
|
|
|
Description
Growth hormone (GH) is a monomeric protein produced and stored in somatotrophs in the anterior pituitary gland. GH is released from the pituitary into the bloodstream in a pulsatile manner under the regulatory control of hypothalamic somatostatin (SS) and GH-releasing factor (GHRF) [1]. The timing and frequency of GH release appears to be regulated by somatostatin, while the amplitude of GH release is determined by GHRF. GH has profound effects on tissue growth and metabolism, which is thought to be mediated through GH-dependent production of IGF-I and IGF-II, and their associated binding proteins. GH apparently stimulates IGF production after binding to specific cell surface receptors in the liver and, possibly, other tissues. Almost 50% of GH in circulation is bound to a high affinity GH binding protein (GHBP), which represents the extracellular domain of the GH receptor.
References
Iranmesh A, et al. J Clin Endocrinol Metab 73:1081-1088, 1991.