Rabbit Anti-Human ACAT2 Polyclonal Antibody, Unconjugated
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GenWay Biotech, Inc.
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Product
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Rabbit Anti-Human ACAT2 Polyclonal Antibody, Unconjugated
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Company
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GenWay Biotech, Inc.
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Price
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Pricing Info
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More Information
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View Company Product Page
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Target
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ACAT2
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Catalog Number
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18-003-42288-0.1 mg
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Quantity
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0.1 mg
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Species
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Human
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Reactivity
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Human
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Conjugate/Tag/Label
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Unconjugated
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Applications
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Immunohistochemistry-P, Western Blot
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Host
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Rabbit
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Type
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Polyclonal Antibody
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Isotype
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IgG
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Form
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Purity: Rabbit IgG purified by protein A chromatography.
Format: Suggested dilution at 2.0 µg/ml in 5% skim milk / PBS buffer. and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50.000 - 100.000 as second antibody.
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Original Item Name
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ACAT2 (acetyl-Coenzyme A acetyltransferase 2 (acetoacetyl Coenzyme A thiolase))
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Description
Acetyl-Coenzyme A acetyltransferase 2 is an enzyme involved in lipid metabolism. Reported patients with ACAT2 deficiency have shown severe mental retardation and hypotonus. The ACAT2 gene shows complementary overlapping with the 3-prime region of the TCP1
Catalytic Activity: 2 acetyl-CoA = CoA + acetoacetyl-CoA.
Subunit: Homotetramer.
Subcellular Location: Cytoplasm.
Similarity: Belongs to the thiolase family.
Summary: The product of this gene is an enzyme involved in lipid metabolism, and it encodes cytosolic acetoacetyl-CoA thiolase. This protein shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation.
Product ID: 42288
GI Number: 148539872
Accession Number: NP_005882.2
Sp Accession Number: Q16146
OMIM: 100678
Sequence Length: 397
Molecular Weight: 41351
NCBI Name: Acetyl-Coenzyme A acetyltransferase 2; Acetyl-CoA acetyltransferase, cytosolic
Cross-Reactivity: Human
Testing Protocols: IHC: 18-003-42288_IH, WB: 18-003-42288_WB
Storage: Antibody is lyophilized from PBS buffer with 2% sucrose. Add 100 µl of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage. store at -20C.
Stability: Note: Avoid repeat freeze-thaw cycles.
Antigen Specificity: Polyclonal antibody produced in rabbits immunized with a synthetic peptide from human ACAT2.
ELISA Titre: 1:312500
Note: Suggested starting concentrations are provided. Optimal dilutions should be determined by end-user. Differences in calculated versus apparent molecular weight may be due to post-translational modifications or protein hydrophobicity.
Interaction: P63092, EBI-1047273, EBI-1047114
References
Sakashita.N.et al. (2003) Lab.Invest.83(11).1569-1581.