Custom Peptide Synthesis
from
BACHEM
Description
If it’s got to be quality, it’s got to be Bachem! See the list of modifications we offer.
Bachem has the most peptide chemists in the industry. We have almost 40 years experience in designing and synthesizing novel peptides and related organic compounds according to customer requirements.
* Research to commercial scale quantities
* Non-GMP to GMP quality
* Short peptides to small synthetic proteins
* Peptides to peptidomimetics to complex organic molecules
We are proficient in solution phase peptide synthesis and solid phase peptide synthesis, using Fmoc or Boc chemistries.
The following frequently requested modifications are available at Bachem:
* Acetylation, acylation (e.g. lipopeptides), biotinylation and formylation
* Amidation
* Thioethers, hydroxyethylene isosteres, retro-inverso peptides
* Cyclizations: single or multiple disulfide bridges, head to tail and side chain (lactam bridge, thioether)
* Phosphorylation, sulfatation and glycosylation
* Incorporation of chromophores
* Fluorescent dyes/fluorogenic groups
* Fluorophore/quencher pairs
* Conjugation to a carrier protein
* Incorporation of D-enantiomers and unusual amino acids
* Labeling with stable isotopes and radiolabeling
* Introduction of C-terminal alcohol moieties
* Introduction of C-terminal ester and thioester groups
* Depsipeptides
* Stabilizing modifications including PEGylation, N-methylated amino acids and reduced peptide bonds
* Ligations
* Hydrocarbon-stapled peptides
* Conjugation of cytotoxic molecules
* Incorporation of chelating moieties (DOTA, DPTA)
When your project requirements advance from research scale to process development and cGMP manufacturing, Bachem is ready to support you with our framework of cGMP production facilities and dedicated regulatory affairs staff.