15(S)-Latanoprost
from
Cayman Chemical
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Product
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15(S)-Latanoprost
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Company
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Cayman Chemical
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Price
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Pricing Info
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More Information
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View Company Product Page
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Conjugate/Tag/Label
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Unconjugated
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Molecule Name
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15(S)-Latanoprost
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Original Item Name
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15(S)-Latanoprost
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Target/Molecule Synonym
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15-epi Latanoprost
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Catalog Number
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16818
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Quantity
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5 mg
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Description
15(S)-Latanoprost is an analog of latanoprost in which the hydroxyl at carbon 15 is inverted relative to latanoprost. The IC50 values for the free acid forms of latanoprost and 15(S)-latanoprost were determined to be 3.6 nM and 24 nM, respectively, in a FP receptor binding assay using the cat iris sphincter muscle. A 3 µg dose of 15(S)-Latanoprost caused a 1 mmHg reduction of IOP in normotensive cynomolgus monkeys. 15(S)-latanoprost is a potential impurity in most commercial preparations of the latanoprost bulk drug product.