TNF alpha Antibody

July 27, 2017

Pathology
The University of Utah
Graduate Research Assistant

Overall

Quality of Results

Ease-of-Optimization

What do these ratings mean?
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Company:

Bio X Cell

Product Name:

InVivoMAb anti-mouse TNFα

Catalog Number:

BE0058-A025mg

Bio X Cell makes great antibodies for in vivo cell depletion and cytokine neutralization. Recently, they've improved the references listed for each antibody they offer, which makes it very easy to determine experimental dosages. This TNFa has consistently provided great results for our lab, and the academic pricing makes it a great value for academic researchers.

Experimental Design and Results Summary

Applications

Block/Neutralize/Inhibit

Sample

Mice infected with Listeria

Primary Incubation

N/A

Blocking Agent

N/A

Secondary Incubation

N/A

Tertiary Incubation

N/A

Detection

BioLegend Legendplex

Results Summary

We saw good, though not complete neutralization, during our infection. We believe that in the future to get complete neutralization we will simply need to increase the amount or frequency of the antibody treatments.

DOI or PMID #

N/A

Additional Notes

N/A

Related Categories

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Summary

The Good

Easy to use and well-documented

The Bad

As with everything, there is still the requirement of optimization if you want complete neutralization

The Bottom Line

Bio X Cell is one of the best manufacturers for in vivo antibodies, and this TNF antibody is no different. It gives reproducible results even after months in a fridge, and that's what we want.

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