Cytocell
P53/ATM Aquarius FISH probe
LPH 052
I am investigating chromosomal aberrations in lymphoma and have used the P53/ATM probe to assess gain and loss of these targets from fresh-frozen imprint slides.
FISH for gain and loss
Fresh-frozen imprint slides
The probe was applied directly to the slides, which were incubated for 75C for 2 minutes followed by 37C for 24 hours.The P53 probe is labeled in red and covers the whole P53 gene. The ATM probe is labeled in green, and covers the telomeric end of NPAT gene and the centromeric end of the ATM gene.
DAPI is also supplied
Clear red and green signals, with two copies of each per cell indicating normal status.
Bright and specific FISH probes
Relatively expensive
Reliable probe that indicates gain/loss of two regions simultaneously.
Product Name: P53/ATM Aquarius FISH probeSupplier Page