Upstate
Anti-Kaiso Antibody, clone 6F
05-659
Info: View Product View Product Specs
Kaiso binds to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' and also binds to the non-methylated consensus sequence 5'-CTGCNA-3'. Recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. May contribute to the repression of target genes of the Wnt signaling pathway.
Immunohistochemistry
Mouse colon of APC MIN mouse
1/500
Goat serum 10%
Leyca Powervision
Not needed
DAB
Strong signal in nuclei and/or cytoplasmic region on cells along the villi.
No retrieval needed
Specific signal. strong signal
Any remarkable.
Good detection even wothout retrieva!!nice option to work with!