Library Screening Services

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Axiom® Genomic Database Screening

Affymetrix

Catalog Number: 000785
Description: Axiom® Genomic Database Screening Axiom® Genotyping Services The Affymetrix® Research Services Laboratory (ARSL) provides high-quality and economical processing of your samples. Our service lab has genotyped more than 250,000 samples and called over 60 billion genotypes, enabling our customers to complete their genotyping studies quickly and affordably. Our staff uses expert knowledge of best practices to process and analyze your samples, manage your Axiom Genotyping Services project from start to finish, and meet your crucial deadlines. Axiom® Catalog Array Genotyping Services Our Axiom® Catalog Array Genotyping Services offer hassle-free, high quality data from any existing Axiom® Genome-Wide Array Plate. This includes genotyping services using arrays for a variety of organisms and for a range in number of SNPs from 675,000 to two million. Axiom® myDesign™ Array Genotyping Services Our Axiom® myDesign™ Array Genotyping Services enable you to create fully- or semi-customized genotyping arrays containing 1,500 to 2.6 million markers and then have them processed by ARSL with the same high-quality and fast turnaround time we provide for our catalog arrays. Human Axiom® Genomic Database Screening The Human Axiom® Genomic Database is the worlds largest collection of validated common and rare SNPs. Our screening service enables you to screen your samples against a set of six arrays, encompassing a total of approximately 5 million SNPs, to create custom arrays containing 50,000 to as many as 2.6 million SNPs. These services for human genotyping allow genome-wide, hypothesis-free screening against uncharacterized populations.

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High-Throughput High-Content RNAi Screens

Cenix BioScience GmbH

Catalog Number: HT/HC-custom
Description: Cenix is an industry leader in performing fully customizable high-throughput RNAi Screens in transformed or primary cell models. Since 1999, our well-established core capabilities in high-throughput RNAi screening together with fluorescent reader-based and high-content microscopy-based assays have yielded optimized protocols in a broad and ever-growing collection of cultured cell models, covering a wide range of disease fields including oncology, cardiovascular, metabolic, neurological and infectious diseases. Please contact us to learn how we can add value and efficiency to your next screening project.

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miRNA Inhibitor Library Screening, miRNA Mimic Library Screening

Cenix BioScience GmbH

Catalog Number: miR-custom
Description: Using up-to-date microRNA inhibitor and mimic libraries, Cenix offers cell-based miRNA Screening, for miRNA target or biomarker discovery and validation. Built upon our long-standing expertise in combining high-throughput RNAi screening with high-content multi-parametric assays, we now offer miRNA modulator screens and/or tandem siRNA/miRNA screens in a range of cell models including adult stem cells. To learn more about how Cenix can help you with your miRNA screening project, please contact us.

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siRNA Screening, siRNA Library Screening

Cenix BioScience GmbH

Catalog Number: siRNA-custom
Description: Cenix offers fully customizable siRNA Screens covering a broad range of disease fields including oncology, cardiovascular, metabolic, neurological and infectious diseases, and using transformed or primary human or rodent cell models. Whether focused on a handful of target genes, a certain target class or a genome-wide screen, our 11+ years of well-established core capabilities in high-throughput siRNA screening in combination with multi-parametric microscopy assays have resulted in optimized protocols in a broad and ever-growing collection of cultured cell models. Please contact us to discuss the details of your screening needs.

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Custom made highly complex, domain libraries

Hybrigenics Services SAS

Catalog Number: Discover-Library
Description
: Our libraries are the most complex ones available on the market and ULTImate Y2H™ cell-to-cell mating is the only screening technology that can screen them exhaustively. Should you not find your favourite library among our 50+ libraries, we would be happy to construct it for you.

Our ULTImate Y2H domain libraries are validated by extremely stringent quality controls:
- Verifying a complexity of at least 10 million independent, primary fragments in yeast for Random-Primed cDNA libraries. The complexity of the genomic libraries (constructed for organisms that contain no or few introns) depends on the size of the genome (e.g. 2 million genomic fragments for Helicobacter pylori library)
- Random sequencing of 192 clones to check for i) absence of contamination, ii) that ribosomal RNA, mitochondrial DNA and empty vectors represent less than 10% of the total sequences
- Verifying the viability and mating properties of the library-containing yeast cells, and defining the conditions to obtain the highest mating efficiency (Patent US No 6,187,535)
- Reproducing selected Y2H screen interactions available from the literature.

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Library Screening Service

Rx Biosciences

Catalog Number: Library Screening
Description
: Rx Biosciences offers cDNA, genomic and phage display library screening services using cDNA, oligonucleotide and antibody probes.
Features
- Quick probe preparation by in-house gene synthesis or other conventional methods
- 500 000 to 1000 000 clones screened
- Primary, secondary and tertiary screenings
- Homologous or heterologous probes
- Oligonucleotide probes
- Antibody probes
- Successful and guaranteed results