Microarrays, also known as chips or biochips, consist of a substrate of interest fixed to a solid matrix such as a glass slide, used for genotyping, antibody detection and comparative genome analysis. Microarrays can be produced in house with specialized equipment, or purchased from a manufacturer. Microarray slides or chips are spotted with arrayers, hybridized in ovens, and refined by washers and strainers. Separate components can be purchased to produce, process, scan and analyze microarrays. Entire systems are available for scanning and analysis. A laboratory embarking on microarray experimentation should consider the option of self-produced vs. custom arrays. Arrays made “from scratch” provide a relatively low cost and easily customized microarray for each experiment. Commercially produced arrays have the benefit of reduced labor time and excellent reproducibility. In situ arrays require synthesis of the substrate directly onto the support. Budget, throughput, and available lab space are the important parameters for microarray equipment purchases.
The ImProm-II™ Reverse Transcription System from Promega offers a reliable way ...
Microarray technology has been in use in the scientific community for the past ...
Tuesday, January 08, 2013
RNA-Seq has largely solved many of the problems posed when using microarrays in transcriptome ...
Wednesday, November 14, 2012
Microarrays are arrangements of thousands of biomolecules on a solid substrate, such as a silicon ...
Friday, November 12, 2010
As the first provider for LncRNA (Long non-coding RNA) microarray services, Arraystar Inc.’s goal is to aid researchers in streamlining their LncRNA studies so they can explore and discover new mechanisms, resulting in innovative findings and ...
Wednesday, August 11, 2010
Biological processes are most closely related to regulation and changes at the proteome level. Protein microarrays are useful tools for understanding the proteome and discovering biomarkers. Tecan offers a suite of instruments that standardize and ...
Web Seminar: Sensitive Gene Expression Profiling Using Minimal Amounts of RNA
Sunday, December 09, 2012
A new method for detecting abnormalities in unborn children is providing physicians with more information to analyze the results than conventional, ...
STANFORD, Calif. — Imagine listening to a child plinking out a rudimentary tune on the piano. He uses only one octave and one hand — notes he can't ...
Wednesday, March 21, 2012
Oxford Gene Technology (OGT), provider of innovative clinical genetics and diagnostic solutions to advance molecular medicine, has today released the ...