Quadrupole Mass Spectrometers

Quadrupole Mass Spectrometers A quadrupole mass spectrometer contains four parallel cylindrical rods which can scan or filter sample ions based on their mass-to-charge ratio. Opposing rods are connected electrically and a radio frequency voltage is applied between the pairs of rods. Ions travel between the rods and only ions with a specific mass-to-charge ratio will exit the quadrupole; other ions will collide with the rods. The desired mass-to-charge ratio can be altered by changing the applied voltage. Triple quadrupole mass spectrometry makes use of the same technology, but uses a linear series of three quadrupoles to improve sensitivity and selectivity. This type of spectrometry is useful when studying particular ions of interest since it is able to stay tuned to a single ion for extended periods of time.

Quadrupole Mass Spectrometers

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Thermo Scientific™ Endura™ Triple Quadrupole Mass Spectrometer
  • Catalog Number: IQLAAEGAAXFAPJMBFU
  • Description: From forensic toxicology to environmental analysis to pharmaceutical research, a constant in almost every field is the need for greater productivity; to quantify more samples in less time with greater reliability and confidence, and to do it all on ever tighter budgets. The Thermo Scientific™ Endura™ Triple Quadrupole Mass Spectrometer meets these needs with unsurpassed value. It delivers best-in-class sensitivity run after run and day after day regardless of sample type or matrix, and does so with an ease-of-use that takes the worry out of method development and operation.
  • Mass Analyzer: 10 to 3400 m/z
  • Resolution: 2 FWHM
  • Scanning Speed: Up to 500 SRMs/s
  • Dimensions: (WxDxH) 760 x x 840 x 680 mm
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Thermo Scientific™ Exactive Plus Q Exactive™ Plus Hybrid Quadrupole-Orbitrap™ LC-MS/MS Mass Spectrometer
  • Catalog Number: IQLAAEGAAPFALGMBDK
  • Description: Take Quanfirmation™ to the next level. The Thermo Scientific™ Q Exactive™ Hybrid Quadrupole-Orbitrap™ Mass Spectrometer introduced the revolutionary concept of Quanfirmation. The Q Exactive™ Plus Hybrid Quadrupole-Orbitrap™ Mass Spectrometer takes Quanfirmation to the next level with increased performance and new options that enhance applications from confident DMPK qual/quan screening studies to characterization of intact monoclonal antibodies.
  • Mass Analyzer: Hybrid Quadrupole / Orbitrap
  • Resolution: up to 280,000 FWHM
  • Mass Range: 50 to 6,000 m/z
  • Scanning Speed: Up to 12 Hz
  • Dimensions: Inquire
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Thermo Scientific™ Orbitrap Fusion™ Tribrid™ Mass Spectrometer
  • Catalog Number: IQLAAEGAAPFADBMBCX
  • Description: Meet your most challenging biological research objectives using the Thermo Scientific™ Orbitrap Fusion™ Tribrid™ Mass Spectrometer. This instrument combines the best of quadrupole, ion trap and Orbitrap mass analysis in a revolutionary Tribrid architecture to provide unprecedented depth of analysis and ease of use. Innovative software and instrument design let you concentrate on your science rather than method development and instrument operation.
  • Mass Analyzer: 50 to 2000 m/z (Standard mode)
    200 to 4000 m/z (High Mass mode)
  • Resolution: 450,000 FWHM
  • Scanning Speed: 18 Hz
  • Dimensions: (WxDxH) 1270 x 767 x 703 mm
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Thermo Scientific™ Q Exactive™ Focus Hybrid Quadrupole-Orbitrap Mass Spectrometer
  • Catalog Number: IQLAAEGAAPFALGMBHE
  • Description: The sensitivity, selectivity, flexibility, and ease-of-use provided by hybrid quadrupole-Orbitrap mass spectrometers set the standard for screening, quantitation, identification, and confirmation of targeted and untargeted compounds. The Thermo Scientific™ Q Exactive™ Focus hybrid quadrupole-Orbitrap MS makes this power accessible to environmental, food safety, clinical research, forensic toxicology, and pharmaceutical labs challenged by growing sample volumes and constrained by strict budgets. The Q Exactive Focus system simplifies method development, saving time and decreasing costs while reliably delivering unsurpassed results.
  • Mass Analyzer: 50 to 2000 m/z
  • Resolution: Up to 70,000 FWHM
  • Scanning Speed: 12 Hz
  • Dimensions: (WxDxH) 910 × 830 × 950 mm
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Thermo Scientific™ Q Exactive™ HF hybrid quadrupole-Orbitrap LC-MS/MS System
  • Catalog Number: IQLAAEGAAPFALGMBFZ
  • Description: Identify and quantify more proteins, peptides, lipids, glycans and small molecules accurately and in less time with the Thermo Scientific™ Q Exactive™ HF hybrid quadrupole-Orbitrap mass spectrometer. The Q Exactive HF system combines a state-of-the-art segmented quadrupole for high-performance precursor ion selection with a high-resolution, accurate-mass (HR/AM) ultra-high-field Orbitrap mass analyzer to deliver a superior combination of scan speed, resolving power, mass accuracy, spectral quality and sensitivity. Identify, quantify and confirm in a single analysis with a single instrument with the Q Exactive HF mass spectrometer.
  • Mass Analyzer: Hybrid Quadrupole / Orbitrap
  • Resolution: up to 240,000 FWHM
  • Mass Range: Up to 2,000 m/z
  • Scanning Speed: Inquire
  • Dimensions: Inquire
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Thermo Scientific™ Q Exactive™ HF Hybrid Quadrupole-Orbitrap Mass Spectrometer
  • Catalog Number: IQLAAEGAAPFALGMBFZ
  • Description: Identify and quantify more proteins, peptides, lipids, glycans and small molecules accurately and in less time with the Thermo Scientific™ Q Exactive™ HF hybrid quadrupole-Orbitrap mass spectrometer. The Q Exactive HF system combines a state-of-the-art segmented quadrupole for high-performance precursor ion selection with a high-resolution, accurate-mass (HR/AM) ultra-high-field Orbitrap mass analyzer to deliver a superior combination of scan speed, resolving power, mass accuracy, spectral quality and sensitivity. Identify, quantify and confirm in a single analysis with a single instrument with the Q Exactive HF mass spectrometer.
  • Mass Analyzer: 50 to 6000 m/z
  • Resolution: Up to 240,000 FWHM
  • Scanning Speed: 18 Hz
  • Dimensions: (WxDxH) 910 × 830 × 950 mm
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Thermo Scientific™ Q Exactive™ Hybrid Quadrupole-Orbitrap LC-MS/MS System
  • Catalog Number: IQLAAEGAAPFALGMAZR
  • Description: The Thermo Scientific Q Exactive hybrid quadrupole-Orbitrap mass spectrometer combines high-performance quadrupole precursor selection with high-resolution, accurate-mass (HR/AM) Orbitrap™ detection. The superior quality of Q Exactive™ MS/MS data provides ultimate confidence for a wide range of qualitative and quantitative applications. Its high scan speed and spectral multiplexing capabilities make it fully compatible with UHPLC and fast chromatography techniques, ramping productivity to a new level. The Q Exactive instrument can easily handle routine applications in proteomics from bottom-up protein ID to semiquantitative isotopic labeling analyses to targeted quantification experiments. At the same time, its innovative HR/AM Quanfirmation™ capability makes the Q Exactive mass spectrometer the ideal solution for fast, easy residue screening and quantification in food safety, environmental and toxicology labs. The Q Exactive MS is superbly suited to routine bioanalytical quantitation of both large and small molecules; the superior quality of its HR/AM data supplying an added degree of confidence to these analyses. It is also ideal for pharmaceutical research laboratories looking for confident ID and precise quantification of metabolites, impurities, leachables and extractables. In short, the versatility and high data quality of the Q Exactive LC-MS/MS system make it a valuable addition to any modern laboratory.
  • Mass Analyzer: Hybrid Quadrupole / Orbitrap
  • Resolution: up to 140,000 FWHM
  • Mass Range: Inquire
  • Scanning Speed: Inquire
  • Dimensions: Inquire
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Thermo Scientific™ Q Exactive™ Hybrid Quadrupole-Orbitrap Mass Spectrometer
  • Catalog Number: IQLAAEGAAPFALGMAZR
  • Description: Identify, quantify and confirm more compounds rapidly and with confidence using the Thermo Scientific™ Q Exactive™ Hybrid Quadrupole-Orbitrap Mass Spectrometer. This benchtop LC-MS/MS system combines quadruple precursor ion selection with high-resolution, accurate-mass (HRAM) Orbitrap detection to deliver exceptional performance and versatility. The Q Exactive Mass Spectrometer is equally useful for untargeted or targeted screening and a broad range of qualitative and quantitative applications in drug discovery, proteomics, environmental and food safety, clinical research and forensic toxicology.
  • Mass Analyzer: 50 to 6000 m/z
  • Resolution: Up to 140,000 FWHM
  • Scanning Speed: 12 Hz
  • Dimensions: (WxDxH) 910 × 830 × 950 mm
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Thermo Scientific™ Q Exactive™ Plus Hybrid Quadrupole-Orbitrap™ Mass Spectrometer
  • Catalog Number: IQLAAEGAAPFALGMBDK
  • Description: Take Quanfirmation™ to the next level. The Thermo Scientific™ Q Exactive™ Hybrid Quadrupole-Orbitrap™ Mass Spectrometer introduced the revolutionary concept of Quanfirmation. The Q Exactive™ Plus Hybrid Quadrupole-Orbitrap™ Mass Spectrometer takes Quanfirmation to the next level with increased performance and new options that enhance applications from confident DMPK qual/quan screening studies to characterization of intact monoclonal antibodies.
  • Mass Analyzer: 50 to 6000 m/z
  • Resolution: Up to 140,000 FWHM, 280,000 FWHM with Optional Intact Protein Mode and Enhanced Resolution
  • Scanning Speed: 12 Hz
  • Dimensions: (WxDxH) 910 × 830 × 950 mm
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Thermo Scientific™ TSQ Quantiva Triple Quadrupole Mass Spectrometer
  • Catalog Number: IQLAAEGAAXFAOUMZZZ
  • Description: Continual changes in research and regulatory requirements drive the need for ever-lower limits of detection and quantitation. The Thermo Scientific™ TSQ Quantiva™ Triple Quadrupole Mass Spectrometer uses active ion management to exceed even the most stringent analytical requirements with superb sensitivity, speed, and dynamic range. It does so with an ease of operation — from method development through routine maintenance— that allows users to spend more time thinking about their research and less time worrying about instrument setup and operation.
  • Mass Analyzer: Triple Quadrupole
  • Resolution: Inquire
  • Mass Range: Inquire
  • Scanning Speed: Inquire
  • Dimensions: Inquire
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Thermo Scientific™ TSQ Quantiva™ Triple Quadrupole Mass Spectrometer
  • Catalog Number: IQLAAEGAAXFAOUMZZZ
  • Description: Continual changes in research and regulatory requirements drive the need for ever-lower limits of detection and quantitation. The Thermo Scientific™ TSQ Quantiva™ Triple Quadrupole Mass Spectrometer uses active ion management to exceed even  the most stringent analytical requirements with superb sensitivity, speed, and dynamic range. It does so with an ease of operation — from method development through routine maintenance— that allows users to spend more time thinking about their research and less time worrying about instrument setup and operation.
  • Mass Analyzer: 10 to 1850 m/z
  • Resolution: 2 FWHM
  • Scanning Speed: Up to 500 SRMs/s
  • Dimensions: (WxDxH) 760 x x 840 x 680 mm
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SQ Detector 2

SQ Detector 2

Waters Corporation

  • Catalog Number: 720004059en
  • Description: The Waters SQ Detector 2, the ultimate detector for chromatography is a simple, robust, and versatile mass detector that has been designed to be the perfect UPLC, UPC2 , HPLC, and GC, as well as preparative HPLC and SFC. Its Engineered Simplicity™ design philosophy ensures every analyst can consistently generate the highest quality data with minimal training. The universal ion source architecture provides total flexibility and versatility to maximize experimental choices, enabling LC/MS, SFC/MS, GC/MS, and direct sample analysis on a single platform. This capability allows you to extract the minimum amount of data from the widest range of compounds, whatever your separation requirements.

    Features
    • Ease-of-use - designed to reduce complexity
    • Robustness and Reliability
    • Versatility – the widest range of ionization capabilities
  • Mass Analyzer: Single Quadrupole
  • Resolution: Automatically adjusted (IntelliStart) to desired resolution; the valley between the 2034.63 Da and 2035.63 Da peaks is < 12% of the average height of the two peaks
  • Mass Range: 2 to 3072 m/z
  • Scanning Speed: Up to 15,000 Da/s
  • Dimensions: (WxDxH) 36 x 74 x 59 cm (14 x 29 x 23 in)
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Xevo TQ-S

Xevo TQ-S

Waters Corporation

  • Catalog Number: 720003383en
  • Description: The Waters Xevo™ TQ-S is an analytical tool for quantitative and qualitative UPLC/MS/MS applications. Features include off-axis ion technology, known as StepWave™ to quantify and confirm trace components at the lowest possible levels in the most complex samples, and RADAR™ an information-rich acquisition approach that allows you to collect highly specific quantitative data for target compounds while providing the ability to visualize all other components in the sample matrices. With Xevo TQ-S could develop methods that bring drugs to market faster, identify a broader array of food contaminants, and report reliable forensic data with complete confidence.

    Features
    • Class leading sensitivity and robustness
    • Qualitative information
    • Accelerated method development for sensitive and robust methods
    • Reduces complexity, increases ease of use and ensures the correct result every time
    • The widest range of ionization capabilities
  • Mass Analyzer: Quadrupole (MS1/MS2)
  • Resolution: Automatically adjusted (IntelliStart) to desired resolution;
    The valley between the m/z 2034.63 and m/z 2035.63 peaks is < 12% of the average height of the two peaks.
  • Mass Range: 2 to 2048 m/z
  • Scanning Speed: Up to 10,000 Da/s
  • Dimensions: (WxDxH) 61.0 x 99.5 x 71.1 cm (24.0 x 39.0 x 27.8 in)
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Xevo TQ-S micro

Xevo TQ-S micro

Waters Corporation

  • Catalog Number: 720005046en
  • Description: Overview: The Xevo TQ-S micro incorporates revolutionary design to produce a tandem quadrupole instrument with a small footprint that delivers consistent low levels of quantitation with a wide dynamic range. Robust performance begins in the source with ZSpray geometry, efficiently removing neutral molecules while drawing the ions through the sample cone into the analyzer. The StepWave ion guide in the Xevo TQ-S micro is designed to cope with the challenges in the modern laboratory that are produced by high sample throughput and difficult matrices. Neutrals and gas load are passively removed for enhanced transmission with the ions actively transferred into the mass analyzer, improving sensitivity and robustness. All this is achieved while maintaining an extremely small footprint due to the class-leading compact design of the Xevo TQ-S micro.

    Features
    • Robust performance enabling reproducible detection of analytes at low levels in complex matrices
    • Confidently quantify more analytes using high acquisition rates
    • Accessible sensitivity and method transfer with the Xtended Dynamic Range (XDR) detector
    • Understand sample complexity and improve method development with RADAR
  • Mass Analyzer: Two High-Resolution, High-Stability Quadrupole Analysers (MS1/MS2)
  • Resolution: Automatically adjusted (IntelliStart) to desired resolution; (0.50 Da, 0.75 Da or 1.00 Da FWHM)
  • Mass Range: 2 to 2,048 m/z
  • Scanning Speed: Up to 20,000 Da/s
  • Dimensions: Width: 35.6 cm (14.0 in) Height: 60.0 cm (23.6 in) Depth: 93 cm (36.6 in)
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