In Situ Single-Cell Transcriptomic Imaging in Formalin-fixed Paraffin-embedded (FFPE) Tissues with MERSCOPE
Jiang He, Ph.D.
Monday, November 21, 2022
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Chapters
Introduction
Biological systems are intricately spatially organized
Vizgen brings spatial genomics to labs with the MERSCOPE™ platform
MERSCOPE
MERSCOPE is an end-to-end platform solution-Upstream
MERSCOPE is an end-to-end platform solution-Downstream
Working with MERFISH involves three key stages
MERSCOPE enables ground-breaking research
Profile gene expression in situ, from whole tissue, to sub-cellular
Map cell types, characterize cell function and state in complex tissue
Demonstrating connection and impact at single cell resolution, in situ
MERSCOPE Advantages
Quantitative measurement across a large dynamic range of gene expression
Exceptional detection efficiency
High cell throughput
Compatible with protein co-staining
Rigorously validated in the field
MERSCOPETM imaging in FFPE samples
Methods for tissue preservation
Vizgen’s new proprietary chemistry enables in situ, single-cell transcriptomic imaging in FFPE samples
MERSCOPE FFPE workflow maintains exceptional performance
MERSCOPE FFPE workflow is widely applicable across different sample types
MERSCOPE FFPE workflow is compatible with protein co-staining
MERSCOPE FFPE workflow allows true single cell identification through cell segmentation
Vizgen Data Release Program
Single cell, spatially resolved transcriptomic profiling in FFPE human Tumors with MERSCOPE
Cell type identification and mapping in human breast cancer
Characterize immune cell types in the breast cancer microenvironment
MERFISH publications
What customers are saying
MERSCOPE Advantages
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