Evolution of Modular Automation at Zymergen
Peter Kelly
Tuesday, April 21, 2020
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Chapters
Introduction
Table of Contents
Zymergen aims to be the catalyst for creating a vibrant, sustainable future through biology
Zymergen partners with nature to create never-before imagined products and materials
Zymergen brings better bio-based solutions to market
Three principles drive the design of our platform and our approach to optimizing biology
Zymergen comprehensively explores the genome for sources of strain improvements
Zymergen captures and analyzes powerful datasets that go beyond strain performance
Zymergen predicts performance in bench-scale fermentation from measurements in plates
Experiments require a custom, flexible, and robust Automation Platform
Automation can exists at many levels
At the bench
Stand-alone automation
Zymergen committed to Tecan EVO as a go-to liquid handler
The flexible and evolving nature of our processes made script maintenance a challenge
Scaling a fleet of Tecan EVOs
Towards increased versatility: Tecan Fluent
Automation can exists at many levels
Integrated automation
Integrated automation is useful but challenging
Zymergen needed a new level of automation for:
Our Solution
Reconfigurable Automation Carts (RACs)
RACs decentralize plate transportation
RACs can be (re)arranged for any space
RACs can be swapped in a few minutes
Modular systems can be scaled or changed as needed
Liquid Handling RAC: Tecan Fluent
Modular automation is reshaping our workflows
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