DEPArray™ technology: bringing precision to precision medicine
Nicolò Manaresi, PhD
Monday, November 28, 2016
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Chapters
Introduction
DEPArray™ digital sorting
Scientific Reports
DEPArray™ NxT: boost the power of Next Generation Sequencing
Mainstreming DEPArray™ on FFPE: Enabling analysis of small biopsies & low tumor content
DEPArray™ OncoSeek panel
DEPArray™ sorting offsets true-variants dilution by normal cells
Purity bring clarity in CNA assessment
DEPArry™ LibPrep: enabling low-input large-scale analysis
Enable extracting digital copy-number analysis
Divide and conquer
Identification of clinically relevant somatic variants by WES of pure samples
Low-pass WGS and WES from pure cells: highly consistent & informative results
Reveal Loss of Heterozigosity(LOH)...
...and homozygous deletions
Scalable workflows & benefit:from Targeted Amplicons to Omics assays
Conclusion
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