QC and Disease Biomarker Assessment Kit for Reliable MRM-based Plasma Protein Analysis
Christoph H. Borchers
Thursday, June 19, 2014
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Chapters
Introduction
Quantitation in Proteomics
Method and Platform QC Kits
Standardization Kit Contents
Sample Prep. and Analysis Strategy
Protein Panel
LC-MRM/MS Requirements
Kit Stability
Daily QC Kit Analysis (#1a)
Monthly Platform Kit Analysis (#1b)
Workflow Performance Kit Analysis
Biomarker Assessment Kit (BAK)
Sample Prep. Details
Protein Panel
LC-MRM/MS Details
Representative XIC
Quant Criteria and Examples
Quantitation Range
Analytical and Quant Reproducibility
QUALIS: Automatic Data Analysis
Quality Assessment in QUALIS
Quality Assessment for Multiplexed Experiments
Quality Assessment Color Map
Conclusions
Acknowledgements
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