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  • Isolation of RNA from Difficult Samples

    Isolation of RNA from Difficult Samples

    Wednesday, September 22, 2010
    RNA is already notoriously difficult to work with due to its instability, but RNA from “difficult samples” such as fixed tissue, blood, or single ... read more
  • Epigenetics

    Epigenetics

    Wednesday, September 08, 2010
    Within each human genome is a record of that individual's genetic past, and a glimpse into their future. Yet it is only a glimpse. A few high-profile ... read more
  • DNA Methylation Analysis

    DNA Methylation Analysis

    Monday, October 05, 2009
    What distinguishes a liver cell from a neuron? Fundamentally, it's all in the DNA. Not the genetic content per se – the two cells are identical on ... read more
  • RNA Purification

    RNA Purification

    Friday, September 04, 2009
    There is a saying in many labs: “Garbage in, garbage out”. Since what goes “in” to so many assays, arrays, and reactions is RNA, you want to be sure ... read more
  • Plasmid DNA Purification

    Plasmid DNA Purification

    Friday, July 03, 2009
    So many labs use plasmid DNA – in applications such as PCR, transfection, cloning, and sequencing – that it’s no wonder there are many good ... read more
  • Kits for Methylation Detection

    Kits for Methylation Detection

    Friday, April 17, 2009
    DNA methylation is an important epigenetic mechanism, and its study is becoming increasingly popular in biological research. Methylation status is ... read more
  • Epigenetics: Tools For Digging Into Molecular Interactions

    Epigenetics: Tools For Digging Into Molecular Interactions

    Monday, January 26, 2009
    The intriguing field of epigenetics studies heritable changes in phenotype that are not a result of a change in genotype, or DNA sequence. Instead, ... read more
  • Methylation Detection

    Methylation Detection

    Monday, April 07, 2008
    We all know that DNA mutations can cause phenotypic changes—but what about genetic regulations that aren’t caused by a sequence change, so-called ... read more