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  • Cell Signaling Assays

    Cell Signaling Assays

    Wednesday, November 17, 2010
    Though often modeled in isolation, cells are social creatures. Like a teenager with unlimited texting, they send and receive a steady stream of ... read more
  • Fluorophores for Fluorescent Microscopy

    Fluorophores for Fluorescent Microscopy

    Monday, October 18, 2010
    Flip through any biological science journal today and chances are good you'll find at least one fluorescent micrograph. Painted in bright splashes of ... read more
  • in vivo Imaging

    in vivo Imaging

    Monday, July 26, 2010
    When it comes to animal research, there's no getting around one simple fact: It's expensive. Between care, housing, and feeding, live animals can take... read more
  • Fluorescent Western Blotting

    Fluorescent Western Blotting

    Monday, June 28, 2010
    It's been nearly 30 years since W. Neal Burnette first coined the term "Western blotting" to describe the electrophoretic transfer of protein gels ... read more
  • The Western Blotting Workflow

    The Western Blotting Workflow

    Wednesday, February 10, 2010
    Among molecular biologists and protein chemists, few techniques get as much play as the Western blot. Used to assess the presence, abundance, or ... read more
  • Non-radioactive Ligand Binding Assays

    Non-radioactive Ligand Binding Assays

    Monday, September 28, 2009
    Radioactive labels for ligands have long been a part of the biological laboratory repertoire. Radioactivity gives a clear, unmistakeable signal, and ... read more
  • General Lab Equipment

    General Lab Equipment

    Friday, September 11, 2009
    Lab equipment fundamentally comes in two flavors. There's the stuff researchers need to drive their specific projects – mass spectrometers, say, or ... read more
  • Kinase Assays

    Kinase Assays

    Monday, September 07, 2009
    There are 518 protein kinases in the human kinome, and each one tells a story. They are stories of cellular communication and developmental ... read more
  • Western Blotting Antibodies

    Western Blotting Antibodies

    Friday, July 24, 2009
    The core of a conventional Western blot is a pair of antibodies which bring together the analyte of interest and a method of detection. Traditionally.... read more
  • Western Blotting: Techniques For Quantifying Smaller Amounts

    Western Blotting: Techniques For Quantifying Smaller Amounts

    Monday, June 22, 2009

    Though there are many ways to detect proteins, the decades-old technique of western blotting remains a protein detection mainstay. “Western blotting

    ... read more
  • Next Generation Sequencing

    Next Generation Sequencing

    Monday, June 01, 2009
    When does the next generation of sequencing come to a close, marking the start of a newer one? Though the slower, trusty Sanger sequencing method is ... read more
  • in vivo Imaging

    in vivo Imaging

    Monday, April 20, 2009
    In vivo imaging is an optical imaging technique which looks deep into the tissues of living test subjects. Applications for in vivo imaging include ... read more
  • Gel Documentation Systems

    Gel Documentation Systems

    Monday, March 23, 2009
    A major problem in the past with DNA and protein gels has been the difficulty in getting good images and data from them. Photographs under white or UV... read more
  • Western Blotting

    Western Blotting

    Monday, November 03, 2008
    If you think you know all about Western blotting – read on. The latest technological developments for Western blotting make it useful in areas where ... read more
  • Next Generation DNA Sequencing

    Next Generation DNA Sequencing

    Monday, September 24, 2007
    Not long ago, science undergraduates only read about the building blocks of DNA in introductory textbooks. These days it is unsurprising for ... read more