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  • Tools for Generating Knockouts

    Tools for Generating Knockouts

    Monday, October 11, 2010
    Knocking out a gene from an animal’s genetic blueprint is a powerful tool—one that has certainly seen improvements since its relatively recent ... read more
  • Epigenetics

    Epigenetics

    Wednesday, September 08, 2010
    Within each human genome is a record of that individual's genetic past, and a glimpse into their future. Yet it is only a glimpse. A few high-profile ... read more
  • Single Cell Technologies

    Single Cell Technologies

    Wednesday, January 13, 2010
    Gene expression studies have deepened our understanding of important cellular functions. However, they often assume that cells of a particular type ... read more
  • Cloning

    Cloning

    Friday, September 18, 2009
    Today’s cloning systems not only make getting your DNA fragment into your vector a simple and straightforward process, they also make it easy to pop ... read more
  • Gene Reporter Assays

    Gene Reporter Assays

    Monday, August 24, 2009
    Reporter gene assays are used in a variety of ways in biological research, from in vivo and in vitro screening to gene expression and cell signaling. ... read more
  • Gene Specific Reagents

    Gene Specific Reagents

    Friday, July 31, 2009
    CD4, IL-2, VEGF, p53, insulin, GKN1 . . . whatever your gene of interest, gene-specific products can help you answer your most pressing research ... read more
  • Apoptosis

    Apoptosis

    Monday, July 20, 2009
    They say death is a part of life. Perhaps nowhere is that more true than at the cellular level, where cell death plays critical roles in development ... read more
  • Tools for Membrane Protein Analysis

    Tools for Membrane Protein Analysis

    Friday, June 05, 2009
    G protein-coupled receptors (GPCRs), integrins, ion channels and virtually every other type of membrane protein are prime research targets. As key ... read more
  • Kits & Reagents for Plant Science

    Kits & Reagents for Plant Science

    Friday, May 15, 2009
    Plant research presents some unique obstacles: lysing the plant cell, for example, in order to gain access to the cell’s organelles, DNA, RNA, and ... read more
  • Gel Stains

    Gel Stains

    Friday, March 06, 2009
    There are many attractive choices available for staining protein and nucleic acid gels. The old standards, coomassie blue and ethidium bromide, are ... read more
  • Real-time PCR: Extracting More Information

    Real-time PCR: Extracting More Information

    Monday, February 09, 2009
    Real-time PCR is a crucial step in many experiments today: to amplify and quantify DNA, to assess mRNA abundance, even to find small sequences changes... read more
  • RT (Reverse Transcriptase)-PCR

    RT (Reverse Transcriptase)-PCR

    Friday, January 30, 2009
    A reverse transcriptase reaction can be complicated by the presence of secondary structure, high GC content, contamination, RNase degradation, ... read more
  • Subcellular Targeting Of Proteins And Drugs

    Subcellular Targeting Of Proteins And Drugs

    Monday, December 01, 2008
    The inside of a cell is an organized place. Cellular maintenance tasks are functionally compartmentalized into organelles, scaffolding, and ... read more
  • Nucleic Acid Electrophoresis

    Nucleic Acid Electrophoresis

    Friday, November 28, 2008
    Nucleic acid electrophoresis is still a fundamental technique in the molecular biology laboratory. All that’s needed to run your gel is agarose, ... read more
  • Phosphoprotein Analysis

    Phosphoprotein Analysis

    Monday, October 20, 2008
    Protein activity depends on shape. Each protein has a characteristic shape, of course, which is a function of its sequence. Sometimes, though, the ... read more
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