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Tools for Inducible Pluripotent Stem Cell Research
Thursday, December 12, 2013
iPSCs are like embryonic stem cells without the embryo. Researchers create them from more differentiated cells by the introduction of a handful of ...
Protein Purification Tools
Friday, July 26, 2013
Whether it’s Western blotting, mass spectrometry (MS), interaction studies or any of the burgeoning fields of subproteomics, to get good results, you ...
De Novo Sequencing
Thursday, June 27, 2013
A growing number of news reports attest to the power of genomic technologies to crack medical mysteries. But here’s the thing about most of these ...
Happy 30th Birthday to PCR
Tuesday, February 19, 2013
Since PCR’s invention in the 1980s by chemist Kary Mullis at the Cetus Corporation, our ability to amplify specific DNA fragments is often taken for ...
Tools for Efficient Next Gen Sequencing Sample Prep
Tuesday, September 11, 2012
Next generation sequencing sample preparation tools are available from both sequencer manufacturers and third-party vendors. These reagent kits ...
Thursday, January 27, 2011
Eukaryotic cells have a dramatic way of removing themselves when their time has come. A pre-planned cellular suicide known as programmed cell death, ...
Next Generation Sequencing
Monday, November 01, 2010
If you want to get a sense of the current state of the high-throughput sequencing market, look no further than this month's news. First, the US ...
Genome-wide Genotyping and Analysis
Wednesday, October 06, 2010
The holy grail of genotyping is to analyze the genetic profile of an individual patient in the clinic, and use the results to target the most ...
Cell Invasion and Adhesion
Monday, September 13, 2010
One of the most complicating factors in cancer research is elucidating how the cells interact with the extracellular materials surrounding them, and ...
Wednesday, September 08, 2010
Within each human genome is a record of that individual's genetic past, and a glimpse into their future. Yet it is only a glimpse. A few high-profile ...
Automated Nucleic Acid Purification—Getting More for Less, and Faster
Wednesday, September 01, 2010
Many biology students remember the introductory lab in which they “purified” some DNA. Looking at the lump of goo that might have originated in ...
Comparative Genomic Hybridization: More Data, More Power
Wednesday, August 25, 2010
Comparative genomic hybridization (CGH) is a long name for a process that has happily become shortened and vastly more productive in the past few ...
Copy Number Analysis
Wednesday, August 04, 2010
Copy number analysis is beginning to supplement or replace older forms of genomic analysis such as SNP analysis and microarray analysis. New ...
Wednesday, July 14, 2010
Ten years after the first draft human genome was announced, genomic science is finally beginning to pay dividends in the healthcare arena. A few ...
High Resolution Melt
Wednesday, June 23, 2010
High resolution melt (HRM) analysis is one of those “why didn’t I think of that?” special twists on basic nucleotide behavior during PCR, in which ...
Wednesday, June 16, 2010
Not that long ago, analyzing the phosphorylation of a given cellular protein could best be described as painful. If a researcher wanted to know ...
P53/ATM Aquarius Hematology FISH Probe
I am investigating chromosomal aberrations in lymphoma and have used the P53/ATM probe to assess gain and loss of these targets from fresh-frozen imprint slides...
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