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  • Happy Birthday To You – PCR is 30 years old

    Happy 30th Birthday to PCR

    Tuesday, February 19, 2013
    Since PCR’s invention in the 1980s by chemist Kary Mullis at the Cetus Corporation, our ability to amplify specific DNA fragments is often taken for ... read more
  • Western Blotting Continues to Evolve

    Western Blotting Continues to Evolve

    Monday, February 04, 2013
    Though Western blotting has for years been an important mainstay for protein researchers, many believe it has yet to reach its full potential. ... read more
  • Five Important Features of a Standard Thermal Cycler

    Five Important Features of a Standard Thermal Cycler

    Monday, November 26, 2012
    Thermal cyclers, also known as thermocyclers or PCR machines, are important basic instruments relied upon in nearly all molecular biology labs and ... read more
  • Stem Cell Research

    Stem Cell Research

    Friday, December 10, 2010
    Between research advances and legal setbacks, scientists in the stem cell community are surely suffering from collective whiplash these days. First, ... read more
  • Gel Documentation Systems: How to Choose the One for You

    Gel Documentation Systems: How to Choose the One for You

    Wednesday, October 27, 2010
    Quick: what are the most frequently used pieces of equipment in your lab? Pipettes probably take the top spot, but gel documentation systems likely ... read more
  • Cell-based Assays: Getting Closer to Physiology

    Cell-based Assays: Getting Closer to Physiology

    Monday, October 25, 2010
    The effect that a drug has on a cell needs to be studied, ultimately, in a cell. Despite the wealth of information that we can glean from molecular ... read more
  • Live Cell Imaging

    Live Cell Imaging

    Wednesday, October 13, 2010
    Imagine you want to understand the rules of American football. If a friend showed you three snapshots taken during one game, would you be able to suss... read more
  • Is Your Laboratory Equipment Working as Hard as You Are?

    Is Your Laboratory Equipment Working as Hard as You Are?

    Monday, October 04, 2010
    A well-equipped life sciences laboratory includes a number of items that are often not that exciting or glamorous, and yet, such basic equipment that ... read more
  • Adventures with Multiplex Real-Time PCR

    Adventures with Multiplex Real-Time PCR

    Wednesday, August 18, 2010
    Multiplexing your real-time or quantitative PCR reactions would save time and work – but are you up for the challenge? The resources are out there to ... read more
  • Protein Electrophoresis

    Protein Electrophoresis

    Monday, August 02, 2010
    The central principles of protein electrophoresis have not changed in the decades since its inception. However, improvements and refinements continue ... read more
  • in vivo Imaging

    in vivo Imaging

    Monday, July 26, 2010
    When it comes to animal research, there's no getting around one simple fact: It's expensive. Between care, housing, and feeding, live animals can take... read more
  • Fluorescent Western Blotting

    Fluorescent Western Blotting

    Monday, June 28, 2010
    It's been nearly 30 years since W. Neal Burnette first coined the term "Western blotting" to describe the electrophoretic transfer of protein gels ... read more
  • High Resolution Melt

    High Resolution Melt

    Wednesday, June 23, 2010
    High resolution melt (HRM) analysis is one of those “why didn’t I think of that?” special twists on basic nucleotide behavior during PCR, in which ... read more
  • Custom Oligos: Little Strings of Bases with Big Ambitions

    Custom Oligos: Little Strings of Bases with Big Ambitions

    Monday, June 14, 2010
    Who would have thought that the humble nucleic acids described decades ago by Watson and Crick would one day be eyed as therapeutic or diagnostic ... read more
  • MicroRNA Expression Analysis

    MicroRNA Expression Analysis

    Wednesday, June 02, 2010
    If you want an inkling of how hot the microRNA field is, just look at miRBase. In April... read more
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