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Three Tips for ChIP Success
Tuesday, January 28, 2014
In theory, ChIP, RIP and MeDIP are simple. In practice, they are anything but. Here we review three key variables to bear in mind as you set about ...
ChIP Methods Move Toward Easier Automation and Increased Sensitivity
Tuesday, February 12, 2013
Chromatin immunoprecipitation (ChIP) is an immunoprecipitation process to identify specific stretches of chromosomal DNA associated with a protein of ...
Chromatin Immunoprecipitation (ChIP) Assays
Monday, August 29, 2011
Suppose you identify a transcription factor that you believe regulates some gene of interest. It’s easy enough to demonstrate this protein is capable ...
Wednesday, April 06, 2011
Check the pages of most biology textbooks or research publications and you're sure to find at least one illustration of gene expression represented in...
Nuclear Receptors: Bringing The Outside World in
Wednesday, April 21, 2010
The power of nuclear receptors should not be underestimated. However, we have yet to understand fully how these fascinating molecules work, though we ...
Autophagy: Finding the Line Between Normal and Diseased
Monday, February 08, 2010
Autophagy – literally, eating oneself ¬– is a crucial recycling function in cells whereby they rid themselves of intracellular matter such as protein ...
Monday, June 29, 2009
For all its information, DNA is biologically inert. The cell must work to propagate its genetic information, using RNA polymerases to transcribe genes...
DNA-Protein Interactions And ChIP Assays
Monday, October 13, 2008
To witness what occurs in a meeting of DNA and protein would be a fantastic voyage for anyone studying gene regulation – or any number of central ...
Clathrin Heavy Chain Antibody
A clean antibody to detect Clathrin heavy chain. High specificity but sensitivity is okay, load 30-40 ug total protein to get a strong signal.
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