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Optimize Your RNAi Experiments
Thursday, October 17, 2013
RNAi is simple in concept yet nuanced in implementation. Key to success is optimization. The right conditions can take your RNAi experiments from ...
Of Noncoding RNA and Epigenetics
Tuesday, July 23, 2013
Whether long, small or micro, noncoding RNAs are not translated into proteins, yet fulfill important regulatory roles in gene expression. Here we ...
Designing the Optimal siRNA
Tuesday, June 11, 2013
Libraries of pre-designed molecules notwithstanding, sometimes you need to design your own siRNA. Perhaps you want to knock down a gene in an organism...
Choosing an siRNA Transfection Reagent
Thursday, May 16, 2013
There are myriad ways to introduce siRNA into the cell, from encoding it in plasmids or viruses (generally as a longer RNA that is then processed by ...
Choosing An Optimal Method for siRNA Preparation
Monday, June 27, 2011
RNA interference (RNAi) – the process of disrupting gene expression such that the gene’s corresponding protein is reduced or “knocked down” – has ...
Monday, September 06, 2010
Small regulatory RNAs, such as microRNAs and the short-interfering RNAs (siRNAs) that drive RNA interference, are not only interesting research ...
Friday, November 06, 2009
RNAi technology has advanced far beyond the speculative phase, and researchers are looking for higher quality siRNA in greater quantities and wider ...
TRPC3 Staining in Endothelial Cell Surface
Confocal images illustrating localization of TRPC3 channels in the endothelial cell surface of mouse skeletal muscle. Shown are fluorescent images generated by ...
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