Editorial Articles

  • Blend Long and Short Reads for Better mRNA Isoform Analysis

    Transcript Structure by RNA-Seq

    Friday, October 10, 2014
    The average mammalian transcript is between 1,000 and 3,000 bases and exists in multiple forms. Working out the structure and abundance of those ... read more
  • Squeeze More Data from Your Sample with Multiplexed qPCR

    Multiplex qPCR

    Tuesday, April 15, 2014
    Multiplex qPCR commonly used for SNP detection, gene expression and other applications for which a large number of samples, or precious samples, need ... read more
  • Bioinformatics Tools for Gene Expression: Crunching the Numbers

    Software Tools for Gene Expression Analysis

    Thursday, October 24, 2013
    Gene-expression studies yield multitudes of data, and turning those data into biological insights requires software. A variety of options are ... read more
  • Tips for Choosing a qPCR Instrument

    Choosing a qPCR Instrument

    Thursday, September 26, 2013
    qPCR is used for measuring RNA abundance, quantifying pathogen loads and validating microarray and sequencing data, among other applications. First, ... read more
  • RNA Purification: Making the Most of Difficult Samples

    RNA Prep from Problem Samples

    Thursday, August 22, 2013
    Expression analysis has become commonplace. First, though, you need to harvest the RNA. Here are tips for making the most of some difficult sample ... read more
  • Tools for Optimal RNA Prep: From Homogenization and Cell Lysis to Extraction and Purification

    Tools for Optimal RNA Prep: From Homogenization and Cell Lysis to Extraction and Purification

    Wednesday, March 07, 2012
    Extracting and purifying RNA from cells or tissues is no easy task, as anyone needing pure RNA for gene expression analysis will tell you. One of the ... read more
  • Absolute Quantification with Digital PCR

    Absolute Quantification with Digital PCR

    Wednesday, February 22, 2012
    Digital PCR (dPCR) is a dream come true for anyone who has struggled with references and standards in making quantitative PCR (qPCR or real-time PCR) ... read more
  • microRNA Microarrays

    microRNA Microarrays

    Monday, May 02, 2011
    If PubMed is any guide, the microRNA field is smokin' hot. Of the nearly 11,100 references that come up in a search for "microRNA," nearly two-thirds ... read more
  • Epigenetics Tools

    Epigenetics Tools

    Wednesday, April 06, 2011
    Check the pages of most biology textbooks or research publications and you're sure to find at least one illustration of gene expression represented in... read more
  • PCR Cloning

    PCR Cloning

    Friday, February 20, 2009
    PCR cloning is a method of cloning which dramatically reduces the time and effort put into the cloning reaction. A conventional cloning procedure can ... read more
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