Editorial Articles

  • Find Your Target with these MicroRNA Target-ID Tools

    MicroRNA Target ID

    Tuesday, April 08, 2014
    MicroRNAs (miRNAs) affect virtually every aspect of our biology, from cancer to development. Although each of the more than 1,000 known miRNAs can ... read more
  • Chromosomal Translocations and the Hunt for Cancer Biomarkers

    Finding Cancer Biomarkers

    Tuesday, April 01, 2014
    Cancer researchers are constantly on the lookout for ways to predict disease outcome, determine which therapies are called for and track patient ... read more
  • Molecular Cytogenetics Using Next-Gen Sequencing

    Molecular Cytogenetics

    Tuesday, March 11, 2014
    For years, molecular cytogeneticists have been limited by the relatively crude tools at their disposal, such as Giemsa staining, FISH and DNA ... read more
  • Gene Expression Analysis Tools for Non-Model Organisms

    Gene Expression Analysis

    Thursday, February 27, 2014
    Using next-generation DNA sequencing, cloud computing and in silico design tools, anyone can become expert in the gene expression of organisms outside... read more
  • No NGS, No Problem. Outsource Your Analyses with These MicroRNA Service Providers

    Outsourcing miRNA Analysis

    Tuesday, February 18, 2014
    For many researchers, microRNA discovery and investigation are more a means to an end than the focus of their research. Or perhaps they simply are ... read more
  • Probe Noncoding RNA Biology with Protein-lncRNA Interaction Tools

    Probing Protein-lncRNA Interactions

    Tuesday, November 19, 2013
    There is considerable research interest in the class of molecules called long noncoding RNAs (lncRNAs). Many have been identified, but few have had ... read more
  • Making Something From (Almost) Nothing: Whole-Genome Amplification

    Whole Genome Amplification Tools

    Thursday, November 14, 2013
    Typical next-generation sequencing protocols, for example, call for microgram quantities of starting material, far more than may be obtained from many... read more
  • Of Noncoding RNA and Epigenetics

    Of Noncoding RNA and Epigenetics

    Tuesday, July 23, 2013
    Whether long, small or micro, noncoding RNAs are not translated into proteins, yet fulfill important regulatory roles in gene expression. Here we ... read more
  • Detecting Copy-Number Variation at High Resolution

    High-res CNV Detection

    Thursday, June 13, 2013
    Traditionally, geneticists identified CNVs using fluorescence in situ hybridization (FISH) and early microarrays, but those methods had limited ... read more
  • Transcriptome Analysis: Microarrays, qPCR and RNA-Seq

    Transcriptome Tools

    Tuesday, May 21, 2013
    Transcriptomics studies attempt to catalog and quantify the RNA content of a cell, tissue or organism. There essentially are three techniques for ... read more
  • Transcriptomics: From Microarrays to RNA-Seq

    Transcriptomics: From Microarrays to RNA-Seq

    Tuesday, January 08, 2013
    RNA-Seq has largely solved many of the problems posed when using microarrays in transcriptome studies. By sequencing all the transcripts in a sample ... read more
  • The Role of Non-coding RNAs in Epigenetics

    The Role of Non-coding RNAs in Epigenetics

    Sunday, April 01, 2012
    How does the cell direct those epigenetic modifications to where they are needed? The answer seems to involve a class of RNAs called long non-coding ... read more
  • Genomic DNA preparation kits

    Genomic DNA preparation kits

    Monday, April 11, 2011
    The dawn of the kit era, when everything you needed for a routine yet important lab task could be conveniently purchased in a box, made life easier ... read more
  • Copy Number Analysis

    Copy Number Analysis

    Wednesday, August 04, 2010
    Copy number analysis is beginning to supplement or replace older forms of genomic analysis such as SNP analysis and microarray analysis. New ... read more
  • Sequence Capture

    Sequence Capture

    Wednesday, July 14, 2010
    Ten years after the first draft human genome was announced, genomic science is finally beginning to pay dividends in the healthcare arena. A few ... read more
  • Nuclear Receptors: Bringing The Outside World in

    Nuclear Receptors: Bringing The Outside World in

    Wednesday, April 21, 2010
    The power of nuclear receptors should not be underestimated. However, we have yet to understand fully how these fascinating molecules work, though we ... read more