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  • Tools for Identifying DNA Methylation Targets

    Tools for Identifying DNA Methylation Targets

    Tuesday, August 21, 2012
    When it comes to eukaryotic heredity, the genome, as they say, is only the beginning. There’s also the epigenome, a set of heritable chemical ... read more
  • SNP Genotyping Takes Advantage of Faster Sequencing

    SNP Genotyping

    Wednesday, June 06, 2012
    Genetics moves at a dizzying pace these days. Research journals trumpet new genetic associations almost daily for everything from disease ... read more
  • The Role of Non-coding RNAs in Epigenetics

    The Role of Non-coding RNAs in Epigenetics

    Sunday, April 01, 2012
    How does the cell direct those epigenetic modifications to where they are needed? The answer seems to involve a class of RNAs called long non-coding ... read more
  • Tools for Optimal RNA Prep: From Homogenization and Cell Lysis to Extraction and Purification

    Tools for Optimal RNA Prep: From Homogenization and Cell Lysis to Extraction and Purification

    Wednesday, March 07, 2012
    Extracting and purifying RNA from cells or tissues is no easy task, as anyone needing pure RNA for gene expression analysis will tell you. One of the ... read more
  • Absolute Quantification with Digital PCR

    Absolute Quantification with Digital PCR

    Wednesday, February 22, 2012
    Digital PCR (dPCR) is a dream come true for anyone who has struggled with references and standards in making quantitative PCR (qPCR or real-time PCR) ... read more
  • Next Generation Sequencing

    Next Generation Sequencing

    Tuesday, November 29, 2011
    New low-cost instruments, including Life Technologies’ low-cost Ion Torrent PGM and Illumina’s MiSeq, have made next-gen sequencing a possibility for ... read more
  • Genome Editing

    Genome Editing

    Tuesday, October 25, 2011
    If there’s one thing all genome-editing techniques have in common, it’s that they don’t try to reinvent the wheel, molecularly speaking. Rather than ... read more
  • Molecular Cytogenetics

    Molecular Cytogenetics

    Monday, October 17, 2011
    Marrying modern molecular biology with classical cytogenetics, molecular cytogenetics techniques enable researchers to identify chromosomal ... read more
  • Chromatin Immunoprecipitation (ChIP) Assays

    Chromatin Immunoprecipitation (ChIP) Assays

    Monday, August 29, 2011
    Suppose you identify a transcription factor that you believe regulates some gene of interest. It’s easy enough to demonstrate this protein is capable ... read more
  • Epigenetics Tools

    Epigenetics Tools

    Wednesday, April 06, 2011
    Check the pages of most biology textbooks or research publications and you're sure to find at least one illustration of gene expression represented in... read more