Library Construction Services

Library Construction service options are available from several specialized providers. Choosing to outsource this application may not only save time and effort, but can also provide benefits from technical expertise and facilities dedicated to the design, synthesis and production of various libraries. These include cDNA, sgRNA, shRNA, pooled DNA libraries and more. Such services can offer researchers the advantages of large, high-quality libraries that can be customized to specifications. In addition to the desired type of library, among other factors to consider include the intended research application and the sequencing platform.

Library Construction Services

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Sponsored Products

GPCR Libraries

GPCR Libraries

Twist Bioscience

  • Description:
    > 100,000 Different GPCR Binding Motifs
    • With over 100,000 different GPCR binding motifs, unlock the discovery of antibodies to this difficult-to-target class.
    GPCRS ARE HARD-TO-DRUG
    • 30-50% of current drug targets are GPCRs but there are only 2 FDA ...
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Single-Domain Antibody Libraries
  • Description:
    Twist uses four novel VHH methods that combine synthetic and natural approaches to maximize diversity, creating highquality VHH libraries for use against any protein target. These proprietary, naïve single chain domain libraries are ideal for ...
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AbNano&trade; VHH Na&#207;ve Library
  • Description:
    AbNano™ VHH Naïve Library from Fortis Life Sciences® is a fully natural, single domain naïve library with source material from camelids and the antibodies displayed on monovalent phage. It is intended for research purposes only to aid in the ...
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Cloning of Barcode Library from Pre-Made Oligo Pool
  • Description:
    By taking advantage of array-based oligonucleotide synthesis, we can readily make precisely defined large custom pooled libraries expressing many thousands of elements. Within approximately 3 months, we can produce a completely new, high quality ...
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Cloning of CRISPR sgRNA Library from Pre-Made Oligo Pool
  • Description:
    By taking advantage of array-based oligonucleotide synthesis, we can readily make precisely defined large custom pooled libraries expressing many thousands of elements. Within approximately 3 months, we can produce a completely new, high quality ...
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Cloning of shRNA Library from Pre-Made Oligo Pool
  • Description:
    By taking advantage of array-based oligonucleotide synthesis, we can readily make precisely defined large custom pooled libraries expressing many thousands of elements. Within approximately 3 months, we can produce a completely new, high quality ...
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Contract Loss-of-Function Screen with CRISPR sgRNA Library
  • Description:
    The basis of Cellecta’s loss-of-function genetic screening technology is the stable suppression or knockout of specific genes on a large-scale using pooled shRNA or sgRNA libraries in mammalian cell systems. Genetic screens with shRNA or sgRNA ...
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Contract Loss-of-Function Screen with shRNA Library
  • Description:
    The basis of Cellecta’s loss-of-function genetic screening technology is the stable suppression or knockout of specific genes on a large-scale using pooled shRNA or sgRNA libraries in mammalian cell systems. Genetic screens with shRNA or sgRNA ...
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Design and Synthesis of Oligo Pool for Barcode library
  • Description:
    By taking advantage of array-based oligonucleotide synthesis, we can readily make precisely defined large custom pooled libraries expressing many thousands of elements. Within approximately 3 months, we can produce a completely new, high quality ...
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Design and Synthesis of Oligo Pool for CRISPR sgRNA library
  • Description:
    By taking advantage of array-based oligonucleotide synthesis, we can readily make precisely defined large custom pooled libraries expressing many thousands of elements. Within approximately 3 months, we can produce a completely new, high quality ...
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Design and Synthesis of Oligo Pool for shRNA library
  • Description:
    By taking advantage of array-based oligonucleotide synthesis, we can readily make precisely defined large custom pooled libraries expressing many thousands of elements. Within approximately 3 months, we can produce a completely new, high quality ...
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Stable shRNA Knockdown Cell Pool Construction
  • Description:
    By taking advantage of array-based oligonucleotide synthesis, we can readily make precisely defined large custom pooled libraries expressing many thousands of elements. Within approximately 3 months, we can produce a completely new, high quality ...
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ChIP/MeDIP-Seq DNA Library Prep
  • Description:
    Optimized ChIP-seq or MeDIP-seq library preparation service for Illumina platforms.

    Includes: DNA shearing, Adaptor ligation, Library DNA amplification, Bioanalyzer analysis, Amplified library quantification
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Combinatorial Variant Libraries
  • Description:
    Twist Bioscience’s unique capability to synthesize very large numbers of high quality oligos with our massively parallel silicon-based DNA synthesis platform, combined with our well established molecular biology expertise, allow the controlled ...
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Site Saturation Variant Libraries
  • Description:
    Twist Bioscience Site Saturation Variant Libraries leverage massively parallel oligonucleotide synthesis using a silicon-based DNA synthesis platform and extensive molecular biology expertise to systematically and precisely construct variant ...
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Synthetic DNA Libraries

Synthetic DNA Libraries

Azenta Life Sciences

  • Description:
    Cloned pool, linear pool, or individual cloned libraries with a high diversity of functional sequences and precise codon control. High-quality ensured by Sanger sequencing of transformants and NGS-based diversity analysis.
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Chemical Synthesis

Chemical Synthesis

Cayman Chemical

  • Description:
    Our team of synthetic organic and medicinal chemists brings decades of industry experience to perform complex, multi-step organic syntheses. Supported by our Medicinal Chemistry & Structure-Based Drug Design and GMP & Process Development Services, ...
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Custom Compound Libraries

Custom Compound Libraries

Cayman Chemical

  • Description:
    Cayman Chemical offers generation of custom compound libraries.
Hit-to-Lead Optimization

Hit-to-Lead Optimization

Cayman Chemical

  • Description:
    Cayman’s experienced medicinal chemists, structural biologists, and biochemists possess the skills to accelerate your preclinical drug discovery programs with our hit-to-lead optimization services.

    Custom Synthesis & Parallel Library ...
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Medicinal Chemistry

Medicinal Chemistry

Cayman Chemical

  • Description:
    Cayman’s medicinal and computational chemistry services, supported by structure-based drug design (SBDD) and computer-aided drug design (CADD), offer a fully integrated, multidisciplinary approach to developing a wide range of therapeutics. Our ...
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SARS-CoV-2 Targeted Libraries
  • Description:
    Cayman has developed a SARS-CoV-2 Screening Library in which over 70,000 unique drugs and small molecules have been screened in silico for binding to SARS-CoV-2 targets including the spike glycoprotein, proteases, and non-structural proteins (nsps), ...
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Phage Display Library Construction
  • Description:
    Creative Biolabs is pleased to offer customized library construction services under a variety of phage display systems.Our scientists have extensive experience in library construction and are professional in generating different types of phage ...
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