Human Native TLR Genes

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pDUO-hCD14/TLR2

pDUO-hCD14/TLR2

InvivoGen

  • Catalog Number: pduo-hcd14tlr2
  • Description: pDUO-CD14/TLR2 is an expression vector designed to co-express CD14 and TLR2 genes known to interact with each other : human CD14 (1125 bp) and human TLR2 (2352 bp) or murine CD14 (1098 bp) and murine TLR2 (2352 bp). The genes cloned into pDUO comprise the coding sequence (without introns) from the ATG to the Stop codon.
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pDUO-hCD14/TLR4A

pDUO-hCD14/TLR4A

InvivoGen

  • Catalog Number: pduo-hcd14tlr4a
  • Description: pDUO-CD14/TLR4 is an expression vector designed to co-express CD14 and TLR4 genes known to interact with each other : human CD14 (1125 bp) and human TLR4 (2517 bp) or murine CD14 (480 bp) and murine TLR4 (2505 bp). The genes cloned into pDUO comprise the coding sequence (without introns) from the ATG to the Stop codon.
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pDUO-hMD1/RP105

pDUO-hMD1/RP105

InvivoGen

  • Catalog Number: pduo-hmd1rp105
  • Description: pDUO-MD1/RP105 is an expression vector designed to co-express MD1 and RP105 genes known to interact with each other : human MD1 (486 bp) and human RP105 (1983 bp) or murine MD1 (486 bp) and murine RP105 (1983 bp). The genes cloned into pDUO comprise the coding sequence (without introns) from the ATG to the Stop codon.
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pDUO-hMD2/TLR4A

pDUO-hMD2/TLR4A

InvivoGen

  • Catalog Number: pduo-hmd2tlr4a
  • Description: pDUO-MD2/TLR4 is an expression vector designed to co-express MD2 and TLR4 genes known to interact with each other : human MD2 (480 bp) and human TLR4A (2517 bp) or murine MD2 (480 bp) and murine TLR4 (2505 bp). The genes cloned into pDUO comprise the coding sequence (without introns) from the ATG to the Stop codon.
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pDUO-hTLR1/TLR2

pDUO-hTLR1/TLR2

InvivoGen

  • Catalog Number: pduo-htlr1tlr2
  • Description: pDUO-TLR1/TLR2 is an expression vector designed to co-express TLR1 and TLR2 genes known to interact with each other : human TLR1 (2358 bp) and human TLR2 (2352 bp) or mouse TLR1 (2388 bp) and mouse TLR2 (2355 bp). The genes cloned into pDUO comprise the coding sequence (without introns) from the ATG to the Stop codon.
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pDUO-hTLR6/TLR2

pDUO-hTLR6/TLR2

InvivoGen

  • Catalog Number: pduo-htlr6tlr2
  • Description: pDUO-TLR6/TLR2 is an expression vector designed to co-express TLR6 and TLR2 genes known to interact with each other : human TLR6 (2388 bp) and human TLR2 (2352 bp) or murine TLR6 (2418 bp) and murine TLR2 (2352 bp). The genes cloned into pDUO comprise the coding sequence (without introns) from the ATG to the Stop codon.
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pUNO-hTLR1

pUNO-hTLR1

InvivoGen

  • Catalog Number: puno-htlr1
  • Description: Human TLR1 ORF, provided in a pUNO plasmid. pUNO is a family of plasmids expressing genes involved in TLR signaling. pUNO plasmids are selectable in E. coli and mammalian cells with blasticidin.
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pUNO-hTLR10

pUNO-hTLR10

InvivoGen

  • Catalog Number: puno-htlr10
  • Description: Human TLR10 ORF, provided in a pUNO plasmid. pUNO is a family of plasmids expressing genes involved in TLR signaling. pUNO plasmids are selectable in E. coli and mammalian cells with blasticidin.
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pUNO-hTLR2

pUNO-hTLR2

InvivoGen

  • Catalog Number: puno-htlr2
  • Description: Human TLR2 ORF, provided in a pUNO plasmid. pUNO is a family of plasmids expressing genes involved in TLR signaling. pUNO plasmids are selectable in E. coli and mammalian cells with blasticidin.
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pUNO-hTLR3

pUNO-hTLR3

InvivoGen

  • Catalog Number: puno-htlr3
  • Description: pUNO-hTLR3 is a sequence-verified expression plasmid containing the human Toll-like Receptor 3 TLR3 recognizes double-stranded RNA (dsRNA), a molecular pattern associated with viral infection. Stimulation with polyinosine-polycytidylic acid (poly(I:C)), a synthetic analog of dsRNA, was shown to induce hyporesponsiveness in TLR3-deficient mice and marked responsiveness only in 293 cells expressing TLR3, suggesting a specific recognition to poly(I:C) by TLR3. Furthermore, TLR3 signaling is not elicited by either single-stranded RNA (ssRNA) or dsDNA. TLR3 activation induces cytokine production through a signaling pathway dependent on MyD88. Moreover, poly(I:C) can induce activation of NF-?B and mitogen-activated protein kinases independently of MyD88, and cause dendritic cells to mature. Plasmid is selectable in both mammalian cells and E. coli with Blasticidin.
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pUNO-hTLR4A

pUNO-hTLR4A

InvivoGen

  • Catalog Number: puno-htlr4a
  • Description: Human TLR4A ORF, provided in a pUNO plasmid. pUNO is a family of plasmids expressing genes involved in TLR signaling. pUNO plasmids are selectable in E. coli and mammalian cells with blasticidin.
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pUNO-hTLR5

pUNO-hTLR5

InvivoGen

  • Catalog Number: puno-htlr5
  • Description: Human TLR5 ORF, provided in a pUNO plasmid. pUNO is a family of plasmids expressing genes involved in TLR signaling. pUNO plasmids are selectable in E. coli and mammalian cells with blasticidin.
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pUNO-hTLR6

pUNO-hTLR6

InvivoGen

  • Catalog Number: puno-htlr6
  • Description: pUNO-hTLR6 is a sequence-verified expression plasmid containing the human Toll-Like Receptor 6 TLR6 is expressed in spleen and BPL and, similarly to TLR1, acts as a co-receptor. Studies with dominant negative receptors have shown that TLR6 cooperates with TLR2 to recognize peptidoglycan and the yeast cell wall particle, zymosan. Furthermore, TLR6- and TLR2-deficient mice were reported to be hyporesponsive to mycoplasma macrophage-activating lipopeptide-2 kD (MALP-2), a diacylated lipoprotein, suggesting that TLR2 and TLR6 coordinate the response to this ligand. By contrast, TLR2 is able to recognize bacterial lipoproteins triacylated at the N-terminus cysteine residue. Thus TLR6 appears to discriminate between the N-terminal lipoylated structures of MALP-2 and lipopeptides derived from other bacteria. Plasmid is selectable in both mammalian cells and E. coli with Blasticidin.
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pUNO-hTLR7

pUNO-hTLR7

InvivoGen

  • Catalog Number: puno-htlr7
  • Description: Human TLR7 ORF, provided in a pUNO plasmid. pUNO is a family of plasmids expressing genes involved in TLR signaling. pUNO plasmids are selectable in E. coli and mammalian cells with blasticidin.
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pUNO-hTLR8

pUNO-hTLR8

InvivoGen

  • Catalog Number: puno-htlr8
  • Description: Human TLR8 ORF, provided in a pUNO plasmid. pUNO is a family of plasmids expressing genes involved in TLR signaling. pUNO plasmids are selectable in E. coli and mammalian cells with blasticidin.
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pUNO-hTLR9

pUNO-hTLR9

InvivoGen

  • Catalog Number: puno-htlr9
  • Description: Human TLR9 ORF, provided in a pUNO plasmid. pUNO is a family of plasmids expressing genes involved in TLR signaling. pUNO plasmids are selectable in E. coli and mammalian cells with blasticidin.
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