Measure total and OVA specific IgE levels Ovalbumin (OVA) is widely used for inducing an allergic response in mouse models of allergic asthma. Through T and B cell signaling, IgE production is stimulated and released into the bloodstream where it attaches to receptors on cells such as mast cells and basophils. The cells are then activated upon cross-linking of the IgE with the antigen initiating the allergic cascade. The asthma induction process also results in significantly more anti-OVA IgE levels in the serum of mice. Using MD Bioproducts OVA-IgE and Total IgE ELISAs, you can accurately quantitate the total and OVA-specific IgE levels generated during the immune response.
IgE ELISAs
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