Introducing single- and double-stranded oligonucleotides (RNA or DNA) into primary or transformed cell lines has been primarily accomplished through the use of cationic lipid reagents. While these reagents work well for many cell lines, they can suffer from being either toxic at high concentrations or can invoke an immune response in certain cell types. IDT now offers a peptide-based transduction delivery method called Transductin™ that uses the cell’s own mechanism for uptake. Therefore, Transductin™ is able to avoid the toxicity and immune response often observed with other reagents and at a concentration much closer to that of lipid reagents.
Transductin™ siRNA Delivery Reagent
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