New “next-generation” sequencing platforms, capable of generating massive amounts of reads very quickly, can be more effectively utilized for systematic study of genetic variation by analyzing only certain targeted regions (subsets) rather than entire complex genomes. µParaflo® technology enables sequence capture of targeted regions through massively parallel synthesis of high quality DNA on biochips. Genomics samples can be applied directly to the biochip via microfluidics for on-chip sequence capture. Alternatively, the oligonucleotides can be cleaved from the chip, attached to magnetic beads via a 5’ terminal modification, and mixed with genomic samples to perform sequence capture in solution.
Targeted Sequencing - Sample Enrichment Service
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