For many years, CD4+ T-helper cells (Th) were classified as Th1 or Th2, depending on the types of cytokines they produced. Subsequent research revealed a third subset, the regulatory T cell (Treg) and in 2005, a fourth Th lineage was discovered and named Th17 based on expression of the cytokine IL-17. Similar to other Th lineages, a “master-regulator” transcription factor was identified, retinoic acid receptor-related orphan receptor γ (isoform t) (RORγ(t)), that is critical for lineage specification of Th17 cells. eBioscience is pleased to provide the FIRST antibody (clone AFKJS-9) for the detection of RORγ(t) by flow cytometry.
anti-human/mouse RORγ(t) mAb (clone AFKJS-9)
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