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Steps Involved In Northern Analysis

Steps Involved in Northern Analysis

Although established Northern blotting procedures are up and working in most molecular biology laboratories, Ambion has found ways to considerably improve on standard protocols, resulting in greatly increased Northern sensitivity. We have developed RNase-free reagents optimized for each step of the procedure (Figure 1) to provide complete, high-sensitivity Northern blotting systems.

The steps involved in Northern analysis include:

  • RNA isolation (total or poly(A) RNA)
  • Probe generation
  • Denaturing agarose gel electrophoresis
  • Transfer to solid support and immobilization
  • Prehybridization and hybridization with probe
  • Washing
  • Detection
  • Stripping and reprobing (optional)
Figure 1. Northern Analysis with Ambion Kits.

Ambion Contact Information

Ambion
2130 Woodward
Austin, TX 78744
USA

Customer Service: 512-651-0200

Fax Number: 512-651-0201

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