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Date Published
Title
TKXtra DataFile: Homogenous Tyrosine Kinase Detection Using High Efficiency Fluorescence Polarization
Molecular Devices LLC
Sunday, May 14, 2006
Screening for tyrosine kinase activity can be accelerated using High Efficiency Fluorescence Polarization (HEFP
™
) assays. Molecular Devices TKXtra
™
...
read more
Fluorometric Protease Assays In The SpectraMax Gemini Microplate Spectrofluorometer: Example Using Caspase3 (MaxLine Application Note #35)
Molecular Devices LLC
Sunday, May 14, 2006
Modern assays for proteolytic activity typically use synthetic chromogenic or flu-orogenic peptide substrates. Enzyme selectivity is obtained by ...
read more
LIVE/DEAD Viability/Cytotoxicity Assay For Animal Cells Using The SpectraMax Gemini XS Fluorescence Microplate Reader (MaxLine Application Note #43)
Molecular Devices LLC
Sunday, May 14, 2006
This application note describes the use of the SPECTRAmax
®
GEMINI XS from Molecular Devices to study the performance of the LIVE/DEAD
®
Viability/...
read more
Measurement Of Green Fluorescent Protein In The SpectraMax Gemini XS Spectrofluorometer (MaxLine Application Note #44)
Molecular Devices LLC
Sunday, May 14, 2006
GFP (Green Fluorescent Protein) is an extremely stable protein of 238 amino acids produced by the jellyfish
Aequorea victoria
1
that fluoresces in the ...
read more
Measurement Of Molecular Beacons In The SpectraMax Gemini Spectrofluorometer (MaxLine Application Note #36)
Molecular Devices LLC
Sunday, May 14, 2006
Molecular beacons are fluorogenic oligonucleotide probes developed by Kramerand associates to detect specific nucleic acids in homogeneous solutions.
1
...
read more
Laser Capture Microdissection (LCM) For The Analysis Of Macrophage Gene Expression From Atherosclerotic Lesions
Molecular Devices LLC
Tuesday, April 04, 2006
Macrophage foam cells are integral in the development of atherosclerotic lesions, however gene expression studies are complicated by the cellular ...
read more
Laser Capture Microdissection (LCM) And Expression Profiling Of Long-Range Projection Neurons
Molecular Devices LLC
Tuesday, April 04, 2006
Brain tissue is notoriously heterogeneous, and accurate analysis of neural gene expression requires procurement of specific cell types. In this ...
read more
Microgenomic Expression Profiling
Molecular Devices LLC
Tuesday, April 04, 2006
Microgenomic technologies enable expression array analysis from extremely limited cell mass. An integrated system of specialized separation techniques...
read more
Differential Gene Expression Analysis Of Pure Cell Populations From Frozen UterineTissue Using Laser Capture Microdissection (LCM) And CDNA Microarrays
Molecular Devices LLC
Tuesday, April 04, 2006
Laser Capture Microdissection (LCM) is an innovative technique which permits the rapid and reliable procurement of pure cell populations from ...
read more
A Novel Process For Gene Expression Profiling Of Rat And Mouse Tissues From Formalin-Fixed Paraffin-Embedded Sections Using Microarrays
Molecular Devices LLC
Tuesday, April 04, 2006
This application note describes a method for extracting and isolating total RNA from rodent tissues that have been fixed in formalin and embedded in ...
read more
Laser Capture Microdissection Of Muscle Fiber Populations And Expression Analysis By RT-PCR
Molecular Devices LLC
Tuesday, April 04, 2006
To locate gene products in distinct muscle fiber populations of different muscle allotypes, a novel protocol was established. A rapid method to ...
read more
Laser Capture Microdissection Of Cells Labeled With Enhanced Green Fluorescent Protein
Molecular Devices LLC
Tuesday, April 04, 2006
This application note describes a Laser Capture Microdissection (LCM) method for the isolation of cells expressing enhanced green fluorescent protein ...
read more
Setting Up A Kinase Profiler With IMAP®
Molecular Devices LLC
Thursday, October 13, 2005
Kinase profiling is a key aspect of lead compound drug discovery. Many suppliers offer a profiling service, but for maximum flexibility as well as ...
read more
Measuring Cell Proliferation With SpectraMax® M5, M2 And Gemini Microplate Readers Using The CyQUANT® Cell Proliferation Assay
Molecular Devices LLC
Wednesday, October 12, 2005
The Molecular Devices SpectraMax M5 and M2, and Gemini XPS and EM are versatile microplate readers whose detection modes include fluorescence ...
read more
High-content Screening Of GPCR Activation With MetaXpress,™ AcuityXpress™ And The Transfluor® Assay System
Molecular Devices LLC
Wednesday, October 12, 2005
G-protein coupled receptors (GPCRs are the largest class of pharmaceutical targets and, as a result, assays for detecting GPCR receptor agonists and ...
read more
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Anti-human HLA-A2 Antibody
BB7.2 is an example of a polymorphic antibody that recognizes epitopes carried by subsets of HLA class I variants. The epitope recognized by BB7.2 lies in the ...
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