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Genome-Wide RNAi Screens with Human and Mouse Pooled shRNA Libraries

Sigma-Aldrich

Wednesday, December 16, 2009

The past few years has witnessed the development of new technological platforms enabling the creation of genome-scale RNAi libraries and methodologies
... read more
shRNA Phenotypic Screen to Identify Gene Targets Contributing to Androgen Independent Prostate Cancer Cell Growth

Sigma-Aldrich

Wednesday, December 09, 2009
For patients presenting with disseminated prostate cancer, the tumor is typically dependent on androgen for growth and therefore responsive to ... read more
High-throughput Screening Of Peptide Substrates For Tyrosine Kinases Featuring Precisio™ Kinases And PEPscreen® Custom Peptide Library

Sigma-Aldrich

Sunday, November 22, 2009
Kinases are large group of proteins modulating a wide variety of cellular events, including differentiation, proliferation, metabolism and apoptosis, ... read more
Prestige Antibodies® As Organelle Markers For Sub–cellular Localization Studies

Sigma-Aldrich

Tuesday, November 10, 2009
Many characterization studies of proteins require the localization of specific cellular structures such as organelles. Co-localization with ... read more
Sigma’s WGA2 And Roche-NimbleGen’s Array...the Complete ChIP-chip Solution

Sigma-Aldrich

Tuesday, July 21, 2009
ChIP-chip analysis, the combination of chromatin immunoprecipitation (ChIP) and microarray technology, is a powerful tool for accurately mapping ... read more
ChIP Protocol To Rapidly Characterize DNA-Protein Interactions

Sigma-Aldrich

Monday, June 15, 2009
In the study of DNA-protein interactions, chromatin immunoprecipitation (ChIP) has emerged as a powerful technique for discovery and characterization ... read more
How Do Pathway Analysis Tools Enable More Efficient Research?

Sigma-Aldrich

Friday, June 12, 2009
Regardless of their field of study, life scientists face some common challenges when they sit down to analyze their data and design their next ... read more
Screening And Profiling Protein Expression In Human Cancer Serum Using Antibody Array Technologies

Sigma-Aldrich

Tuesday, June 02, 2009
There is a growing need for technologies that enable discovery and validation of protein biomarkers in human serum/plasma. Antibody microarrays have ... read more
Development Of Two Multiplex Immunoassays And Preliminary Application In Determining Protein Depletion For Seppro IgY14/SuperMix Columns

Sigma-Aldrich

Tuesday, May 05, 2009
Depletion of moderately-abundant proteins (MAP) from plasma or serum after removal of highly-abundant proteins (HAP) has been accomplished by ... read more
Sigma's GlycoProfile™ Beta Elimination Kit Allows For Deglycosylation Of Glycoproteins With Subsequent Proteomics Analysis

Sigma-Aldrich

Wednesday, April 15, 2009
Glycoproteomics is an expanding field with many challenges. There are several techniques available for deglycosylation to allow the study of the ... read more
Three-Dimensional Cell Culture Matrices
Sigma-Aldrich Corporation

Sigma-Aldrich

Monday, March 30, 2009
Every day scientists are one step closer to discovering safer and more effective drugs, and to replacing damaged or diseased human organs and ... read more
A Screen Of ShRNAs Targeting Tumor Suppressor Genes To Identify Factors Involved In Paclitaxel Sensitivity

Sigma-Aldrich

Thursday, October 25, 2007
RNA interference methodologies have been utilized in small to large scale screening projects. The technology has allowed researchers to perform ... read more
Use Of PEPscreen^® Libraries To Identify CD8 Epitopes Presented During Malaria Infection

Sigma-Aldrich

Thursday, July 12, 2007
Malaria caused by Plasmodium species kills more than one million people per year, 90% of them in sub-Saharan Africa. An understanding of immunity to... read more
Development Of Peptide-based Microarrays For Screening Antibodies From Patients With Autoimmune Diseases

Sigma-Aldrich

Thursday, July 12, 2007
Autoimmune diseases result from an overactive immune response against substances and cells normally present in the body. They include more than 80 ... read more
Cross-clade CD8⁺ T Cell Responses With A Preference For The Predominant Circulating Clade

Sigma-Aldrich

Thursday, July 12, 2007
The genetic diversity of the human immunodeficiency virus (HIV) represents a major impediment towards a successful vaccine development. For example, ... read more

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Genome-Wide RNAi Screens with Human and Mouse Pooled shRNA Libraries

shRNA Phenotypic Screen to Identify Gene Targets Contributing to Androgen Independent Prostate Cancer Cell Growth

High-throughput Screening Of Peptide Substrates For Tyrosine Kinases Featuring Precisio™ Kinases And PEPscreen® Custom Peptide Library

Prestige Antibodies® As Organelle Markers For Sub–cellular Localization Studies

Sigma’s WGA2 And Roche-NimbleGen’s Array...the Complete ChIP-chip Solution

ChIP Protocol To Rapidly Characterize DNA-Protein Interactions

How Do Pathway Analysis Tools Enable More Efficient Research?

Screening And Profiling Protein Expression In Human Cancer Serum Using Antibody Array Technologies

Development Of Two Multiplex Immunoassays And Preliminary Application In Determining Protein Depletion For Seppro IgY14/SuperMix Columns

Sigma's GlycoProfile™ Beta Elimination Kit Allows For Deglycosylation Of Glycoproteins With Subsequent Proteomics Analysis

Three-Dimensional Cell Culture Matrices
Sigma-Aldrich Corporation

A Screen Of ShRNAs Targeting Tumor Suppressor Genes To Identify Factors Involved In Paclitaxel Sensitivity

Use Of PEPscreen^® Libraries To Identify CD8 Epitopes Presented During Malaria Infection

Development Of Peptide-based Microarrays For Screening Antibodies From Patients With Autoimmune Diseases

Cross-clade CD8⁺ T Cell Responses With A Preference For The Predominant Circulating Clade

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