Apoptosis

Apoptosis With the wide variety of tools currently available and in the works, scientists can assess apoptosis in individual and populations of cells, in samples from live animals to formalin fixed and paraffin embedded (FFPE) microtome slices. Light or fluorescent microscopes, flow cytometers, or spectrophotometers are used for assay detection, and to interrogate parameters ranging from RNA and protein expression, to histone modification, to plasma membrane phospholipid orientation, to membrane potential. The study of apoptosis' defective processes have been associated with a variety of diseases such as cancer. Assay can be outsourced to service facilities or brought in house with custom reagents or pre-made apoptosis assay kits.

  • High-Throughput Caspase Assays

    You'll See Dead Cells (They're Everywhere) with High-Throughput Caspase Assays
    Thursday, June 26, 2014
    Researchers have several options for measuring caspase activity, including at high throughput. Here ...
  • TUNEL Assays for Apoptosis

    Watch Cells Die with These TUNEL Assay Kits
    Thursday, April 10, 2014
    One established hallmark of apoptosis is DNA fragmentation, commonly measured using the terminal ...