Description
Product Characteristics:
Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified.
Subcellular location: Cytoplasm, Nucleus
Synonyms: ICKTyr159, 2210420N10Rik, AI848300, ECO, ICK_HUMAN, Heart serine threonine protein kinase, hICK, Intestinal cell MAK like kinase, Intestinal cell kinase, KIAA0936, Laryngeal cancer kinase 2, LCK2, MAK-related kinase, MAK related kinase, MGC46090, mICK, MRK, OTTMUSP00000041856, OTTMUSP00000041857, Serine/threonine-protein kinase ICK, Serine/threonine protein kinase ICK.
Target Information: Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified. [provided by RefSeq, Jul 2008]