Description
Product Characteristics:
E74 ike Factor 1 is a transcription factor that may be required for the T-cell receptor mediated activation of HIV2 gene expression. It binds to two purine-rich motifs in the HIV-2 enhancer and transcriptionally activates the LYN and mouse BLK promoters.
Subcellular location: Nucleus
Synonyms: mElf 1, E74 like factor 1, ELF 1, ELF1, Ets domain transcription factor, ETS related transcription factor Elf 1, ETS related transcription factor Elf1, p70, Sts1, TRANSCRIPTION FACTOR ELF 1, ELF1_HUMAN.
Target Information: This gene encodes an E26 transformation-specific related transcription factor. The encoded protein is primarily expressed in lymphoid cells and acts as both an enhancer and a repressor to regulate transcription of various genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009]