Description
Product Characteristics:
HERC3 is a member the HERC ubiquitin ligase family. The encoded protein is located in the cytosol and binds ubiquitin via a HECT domain. Mutations in this gene have been associated with colorectal and gastric carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Subcellular location: Cytoplasm
Synonyms: HECT domain and RCC1 like domain containing protein 3, Hect domain and RLD 3, HERC 3, KIAA0032, Probable E3 ubiquitin protein ligase HERC3, HERC3_HUMAN.
Target Information: This gene encodes a member the HERC ubiquitin ligase family. The encoded protein is located in the cytosol and binds ubiquitin via a HECT domain. Mutations in this gene have been associated with colorectal and gastric carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2012]