Description
Product Characteristics:
CHORDC1
Subcellular location: Cytoplasm, Nucleus, Secreted, Extracellular matrix
Synonyms: CHORD containing protein 1, Chord domain containing protein 1, CHORD domain-containing protein 1, CHORD-containing protein 1, CHORDC1, CHP-1, CHP1, CHRD1_HUMAN, Cysteine and histidine rich domain (CHORD) containing 1, Cysteine and histidine rich domain (CHORD) containing, zinc binding protein 1, Cysteine and histidine rich domain containing 1, Cysteine and histidine rich domain containing zinc binding protein 1, Cysteine and histidine-rich domain-containing protein 1, FLJ37289, Protein morgana.
Target Information: Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. Involved in stress response. Prevents tumorigenesis (By similarity)