Description
Product Characteristics:
HENMT1
Subcellular location: Cytoplasm
Synonyms: C1orf59, HEN1, HEN1 methyltransferase homolog 1 (Arabidopsis), HEN1 methyltransferase homolog 1, HENMT_HUMAN, Henmt1, RP11-256E16.2, Small RNA 2''-O-methyltransferase,
Target Information: Methyltransferase that adds a 2'-O-methyl group at the 3'-end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'-end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis (By similarity)