IL-4 Antibody MAB404-100 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemIL-4 Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMAB404-100
Quantity100 ug (also 500 ug, 25 ug)
ApplicationsWestern Blot, Neutralization, ELISA Capture (Matched Antibody Pair)
Conjugate/TagUnconjugated
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ReactivityMouse
TargetIL-4
IsotypeIgG1
Clone30340
HostRat
ImmunogenE. coli-derived recombinant mouse IL-4, His23-Ser140, Accession # P07750
NCBI Full Gene Nameinterleukin 4
NCBI Gene AliasesIl-4, BSF-1
ClonalityMonoclonal
PurityProtein A or G purified from hybridoma culture supernatant
Brand/TrademarkR&D Systems, a Bio-Techne Brand
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

Specificity: Detects mouse IL-4 in ELISAs and Western blots

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Interleukin-4 promotes microglial polarization toward a neuroprotective phenotype after retinal ischemia/reperfusion injuryNeural regeneration researchDecember 1, 2022Chen D, Peng C, Ding XM, Wu Y, Zeng CJ, Xu L, Guo WY.

(2) EC-18 prevents autoimmune arthritis by suppressing inflammatory cytokines and osteoclastogenesisArthritis research & therapyNovember 17, 2022Park JS, Yang SC, Jeong HY, Lee SY, Ryu JG, Choi JW, Kang HY, Kim SM, Hwang SH, Cho ML, et al.

(3) IFN-γ-independent control of M. tuberculosis requires CD4 T cell-derived GM-CSF and activation of HIF-1αPLOS PathogensJuly 25, 2022Erik Van Dis, Douglas M. Fox, Huntly M. Morrison, Daniel M. Fines, Janet Peace Babirye, Lily H. McCann, Sagar Rawal, Jeffery S. Cox, Sarah A. Stanley(1150-ML), 5 U/mL IL-12 p70 from PeproTech (210–12), and 1 μg/mL rat anti-mouse IL-4 from R&D Systems (MAB404100) was added; for Th17.1s, 2 ng/mL TGF-β from Invitrogen (14834262), 20 ng/mL IL-6 from PeproTech (216–16),

(4) Depletion of Foxp3(+) regulatory T cells augments CD4(+) T cell immune responses in atherosclerosis-prone hypercholesterolemic miceHeliyonJuly 1, 2022Kasahara K, Sasaki N, Amin HZ, Tanaka T, Horibe S, Yamashita T, Hirata KI, Rikitake Y.

(5) The YAP/HIF-1α/miR-182/EGR2 axis is implicated in asthma severity through the control of Th17 cell differentiationCell & bioscienceMay 12, 2021Zhou J, Zhang N, Zhang W, Lu C, Xu F.

(6) Ablation of RhoA impairs Th17 cell differentiation and alleviates house dust mite-triggered allergic airway inflammationJournal of leukocyte biologyNovember 1, 2019Yang JQ, Kalim KW, Li Y, Zheng Y, Guo F.

(7) Characterization of the immune response elicited by the vaccinia virus L3 protein delivered as naked DNAVaccineApril 5, 2018Ramírez M, Santos S, Martínez O, Rodríguez R, Miranda E, Ramos-Perez WD, Otero M.

(8) Intraperitoneal infusion of mesenchymal stem cell attenuates severity of collagen antibody induced arthritisPloS oneJanuary 1, 2018Nam Y, Jung SM, Rim YA, Jung H, Lee K, Park N, Kim J, Jang Y, Park YB, Park SH, et al.

(9) Armc5 deletion causes developmental defects and compromises T-cell immune responsesNature communicationsFebruary 7, 2017Hu Y, Lao L, Mao J, Jin W, Luo H, Charpentier T, Qi S, Peng J, Hu B, Marcinkiewicz MM, et al.

(10) ROCK2 signaling is required to induce a subset of T follicular helper cells through opposing effects on STATs in autoimmune settingsScience signalingJuly 19, 2016Weiss JM, Chen W, Nyuydzefe MS, Trzeciak A, Flynn R, Tonra JR, Marusic S, Blazar BR, Waksal SD, Zanin-Zhorov A.8 µg/ml) in the presence of anti-mouse IFN-γ (#MAB485-100, R&D Systems Inc.) and anti-mouse IL-4 (#MAB404-100, R&D Systems Inc.) antibodies together with either mouse IL-21 (10 ng/ml; MN #594-ML-010, R&D Systems Inc

(11) Targeting the binding interface on a shared receptor subunit of a cytokine family enables the inhibition of multiple member cytokines with selectable target spectrumThe Journal of biological chemistrySeptember 11, 2015Nata T, Basheer A, Cocchi F, van Besien R, Massoud R, Jacobson S, Azimi N, Tagaya Y.

(12) Mesenchymal stem/stromal cells protect against autoimmunity via CCL2-dependent recruitment of myeloid-derived suppressor cellsJournal of immunology (Baltimore, Md. : 1950)April 15, 2015Lee HJ, Ko JH, Jeong HJ, Ko AY, Kim MK, Wee WR, Yoon SO, Oh JY.

(13) ROR inverse agonist suppresses insulitis and prevents hyperglycemia in a mouse model of type 1 diabetesEndocrinologyMarch 1, 2015Solt LA, Banerjee S, Campbell S, Kamenecka TM, Burris TP.

(14) TLR2 engagement on CD4(+) T cells enhances effector functions and protective responses to Mycobacterium tuberculosisEuropean journal of immunologyMay 1, 2014Reba SM, Li Q, Onwuzulike S, Ding X, Karim AF, Hernandez Y, Fulton SA, Harding CV, Lancioni CL, Nagy N, et al.

(15) Basophils control T-cell responses and limit disease activity in experimental murine colitisMucosal immunologyJanuary 1, 2014Gomez MR, Talke Y, Hofmann C, Ketelsen I, Hermann F, Reich B, Goebel N, Schmidbauer K, Dunger N, Brühl H, et al.

(16) To investigate the necessity of STRA6 upregulation in T cells during T cell immune responsesPloS oneJanuary 1, 2013Terra R, Wang X, Hu Y, Charpentier T, Lamarre A, Zhong M, Sun H, Mao J, Qi S, Luo H, et al.

(17) Response patterns of cytokines/chemokines in two murine strains after irradiationCytokineMay 1, 2012Zhang M, Yin L, Zhang K, Sun W, Yang S, Zhang B, Salzman P, Wang W, Liu C, Vidyasagar S, et al.

(18) CCL25 induces α₄β₇ integrin-dependent migration of IL-17⁺ γδ T lymphocytes during an allergic reactionEuropean journal of immunologyMay 1, 2012Costa MF, Bornstein VU, Candéa AL, Henriques-Pons A, Henriques MG, Penido C.

(19) The effect of conditional EFNB1 deletion in the T cell compartment on T cell development and functionBMC immunologyDecember 19, 2011Jin W, Qi S, Luo H.

(20) ST2 deficient mice display a normal host defense against pulmonary infection with Mycobacterium tuberculosisMicrobes and infectionApril 1, 2009Wieland CW, van der Windt GJ, Florquin S, McKenzie AN, van der Poll T.

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1/31/2017Mouse IL-4 Antibody Anup KumarI am studying molecular anomalies in signaling pathways leading to cancers and development of anti cancer immune therapies.

IL-4 Antibody

IL-4 Antibody

IL-4 Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (28)

Reviews

IL-4 Antibody from R&D Systems, a Bio-Techne Brand

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