Description
Lysosomal-associated membrane protein 1, also called LAMPA, LGP120 or CD107A, is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. It has also been shown to be a marker of degranulation on lymphocytes such as CD8+ and NK cells. By means of in situ hybridization, Mattei et al.(1990) assigned the gene to chromosome 13q34. Hybridization of LAMP1cDNA to chromosome 12p13.3 was observed even when probes representing different portions of the LAMP1cDNA were used