Goat anti-SDS3 Antibody, Affinity Purified A300-235A from Bethyl Laboratories, Inc. | Biocompare.com

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PLoS genetics
May 01 2012

Fig 1: Differential binding of the AKR and DBA variants of ARID4B to the mSIN3A complex.Western blots (A) show equivalent input of V5-ARID4B, mSIN3A, mSDS3, and equivalent pull-down of the two variants using an anti-V5 antibody. Decreased binding of the DBA variant of ARID4B to mSIN3A and mSDS3 was observed relative to the AKR variant. Experiment was performed in triplicate and densitometry analysis (B) revealed a 51% reduction in mSIN3A binding (p = .037) and a 37% reduction in mSDS3 binding (p = .026) for the DBA variant relative to AKR. Statistical significance was determined using paired t-tests. *, p<.05.

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Bethyl Laboratories, Inc. for
Goat anti-SDS3 Antibody, Affinity Purified

The Goat anti-SDS3 Antibody, Affinity Purified from Bethyl Laboratories, Inc. is a Goat Polyclonal antibody to SUDS3. This antibody recognizes Homo Sapiens, Human, and Mouse antigen. The Goat anti-SDS3 Antibody, Affinity Purified has been validated for the following applications: Precipitation, Immunoprecipitation, and Western Blot.

Description

The epitope recognized by A300-235A maps to a region between residues 175 and 225 of human Suppressor of Defective Silencing 3 using the numbering given in entry NP_071936.2 (GeneID 64426)

Product Specs
ItemGoat anti-SDS3 Antibody, Affinity Purified
CompanyBethyl Laboratories, Inc.
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberA300-235A
Quantity100 µg
ApplicationsWB, IP
Concentration1000 µg/ml
Conjugate/TagUnconjugated
FormatWhole IgG
ReactivityHuman, Mouse
TargetSDS3
HostGoat
Antibody TypePrimary
NCBI Full Gene NameSDS3 homolog, SIN3A corepressor complex component
NCBI Gene AliasesSDS3, SAP45
ClonalityPolyclonal
IsotypeWhole IgG
Domain/Region/Terminusbetween 175 and 225
Storage2 - 8°C

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Bethyl Laboratories, Inc.

Bethyl Laboratories, Inc.

P.O. Box 850

Montgomery, Texas 77356

United States

Phone: 1-800-338-9579
Fax: 1-866-597-6105

Email: orders@fortislife.com

Company Profile

Website: fortislife.com

(1) Human family with sequence similarity 60 member A (FAM60A) protein: a new subunit of the Sin3 deacetylase complexMolecular & cellular proteomics : MCPDecember 1, 2012Smith KT, Sardiu ME, Martin-Brown SA, Seidel C, Mushegian A, Egidy R, Florens L, Washburn MP, Workman JL.

(2) Allelic variation and differential expression of the mSIN3A histone deacetylase complex gene Arid4b promote mammary tumor growth and metastasisPLoS geneticsMay 1, 2012Winter SF, Lukes L, Walker RC, Welch DR, Hunter KW.anti-V5 (1∶5,000; 37–7500, Invitrogen), anti-mSIN3A (1∶1,000; sc-994, Santa Cruz), anti-mSDS3 (1∶2,000; A300-235A, Bethyl Labs), anti-β-actin (1∶10,000; ab6276, Abcam), anti-FLAG (1∶3,000; F-3165, Sigma), anti-HA (1∶5,000;

(3) Breast cancer metastasis suppressor 1 (BRMS1) is stabilized by the Hsp90 chaperoneBiochemical and biophysical research communicationsOctober 6, 2006Hurst DR, Mehta A, Moore BP, Phadke PA, Meehan WJ, Accavitti MA, Shevde LA, Hopper JE, Xie Y, Welch DR, et al.

(4) Cdk5/p35 phosphorylates mSds3 and regulates mSds3-mediated repression of transcriptionThe Journal of biological chemistryDecember 24, 2004Li Z, David G, Hung KW, DePinho RA, Fu AK, Ip NY.

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