Description
Product Characteristics: WDFY3 is a protein which contains WD repeats and an FYVE domain. WDFY3 might target cytosolic protein aggregates for autophagic degradation. Synonyms: Polyclonal WDFY3 antibody, Anti-WDFY3 antibody, WD repeat and FYVE domain containing 3 antibody, ALFY antibody, KIAA0993 antibody, MGC16461 antibody, ZFYVE25 antibody.
Target Information: This gene encodes a phosphatidylinositol 3-phosphate-binding protein that functions as a master conductor for aggregate clearance by autophagy. This protein shuttles from the nuclear membrane to colocalize with aggregated proteins, where it complexes with other autophagic components to achieve macroautophagy-mediated clearance of these aggregated proteins. However, it is not necessary for starvation-induced macroautophagy. [provided by RefSeq, May 2010]