Description
Product Characteristics: The function of this protein remains unknown. Synonyms: Polyclonal Meis3 antibody, Anti-Meis3 antibody, Meis homeobox 3 antibody, Mrg2 antibody.
Target Information: Caudalizing protein which is required to pattern the anterior/posterior (A/P) axis during central nervous system (CNS) formation. Inhibits anterior neural expression and acts as a transcriptional activator to induce posterior neural gene expression. Maintains a proper A/P balance required for hindbrain formation by activating the FGF/MAPK pathway, which modulates the planar cell polarity (PCP) pathway. Interacts with retinoid signaling during hindbrain patterning