The Rabbit Polyclonal to Human GRM3 / MGLUR3 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to GRM3. This antibody recognizes Human, and Non-Human Primate antigen. The Rabbit Polyclonal to Human GRM3 / MGLUR3 Antibody has been validated for the following applications: Immunocytochemistry, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
The Metabotropic Glutamate Receptor GRM3 binds L-glutamate, the major excitatory neurotransmitter in the central nervous system, which activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. Metabotropic glutamate receptor Group II includes the GRM2 and GRM3 receptors that are linked to inhibition of the cyclic AMP signaling cascade