Spring Bioscience's Anti c-Met Antibody (SP44) is a Rabbit monoclonal antibody (clone SP44). The Anti c-Met Antibody (SP44) was generated using c-Met, HGFR, RCCP2, Met Proto-Oncogene, AUTS9, MET as the antigen and it reacts with Human. This antibody has been shown to work in applications such as: Immunohistochemistry.
The c-Met oncogene was originally isolated from a chemical carcinogen-treated human osteogenic sarcoma cell line by transfection analysis in NIH/3T3 cells. The Met proto-oncogene product was identified as a trans-membrane receptor-like protein with tyrosine kinase activity that is expressed in many tissues. The c-Met gene product has been identified as the cell surface receptor for hepatocyte growth factor, a plasminogen-like protein thought to be a humoral mediator of liver regeneration