XBP1 (S Isoform) Antibody MAB4257 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemXBP1 (S Isoform) Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMAB4257
NCBI Gene AliasesXBP-1, TREB-5, XBP2, TREB5
TargetXBP1
IsotypeIgG1
HostMouse
Conjugate/TagUnconjugated
ReactivityHuman
Quantity100 ug (also 25 ug)
ApplicationsIntracellular Staining by Flow Cytometry, CyTOF-ready
Clone525904
NCBI Full Gene NameX-box binding protein 1
ClonalityMonoclonal
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ImmunogenE. coli-derived recombinant human XBP1S, Ser188-Leu287, Accession # NP_001073007
ConcentrationLYOPH
PurityProtein A or G purified from hybridoma culture supernatant
Brand/TrademarkR&D Systems, a Bio-Techne Brand
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

Specificity: Detects human XBP1 (S Isoform) (XBP1S) in direct ELISAs. This segment is found only in the XBP1S (spliced) variant. Does not detect XBP1U (unspliced)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Induction of autophagy-dependent apoptosis in cancer cells through activation of ER stress: an uncovered anti-cancer mechanism by anti-alcoholism drug disulfiramAmerican journal of cancer researchJanuary 1, 2019Zhang X, Hu P, Ding SY, Sun T, Liu L, Han S, DeLeo AB, Sadagopan A, Guo W, Wang X.

(2) Oxytocin modulates markers of the unfolded protein response in Caco2BB gut cellsCell Stress and ChaperonesJuly 1, 2014Benjamin Y. Klein, Hadassah Tamir, David L. Hirschberg, Sara B. Glickstein, Robert J. Ludwig, Martha G. Welchindicate that OT modulates sensors of ER stress and autophagy. CST), mouse mAb anti-spliced XBP1 (MAB4257; R&D Systems), rabbit mAb anti-phospho-IRE1 (Ser724, 3881-1; Epitomics, Burlingame CA), rabbit mAb anti-IRE1

(3) In vivo crystallization of human IgG in the endoplasmic reticulum of engineered Chinese hamster ovary (CHO) cellsThe Journal of biological chemistryJune 3, 2011Hasegawa H, Wendling J, He F, Trilisky E, Stevenson R, Franey H, Kinderman F, Li G, Piedmonte DM, Osslund T, et al.

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XBP1 (S Isoform) Antibody

XBP1 (S Isoform) Antibody

XBP1 (S Isoform) Antibody

XBP1 (S Isoform) Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (3)

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XBP1 (S Isoform) Antibody from R&D Systems, a Bio-Techne Brand

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