Description
Product Characteristics: FUNCTION: Forms a channel for water and glycerol. Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro/Ala-Ala/Ser (NPA). SUBCELLULAR LOCATION: Cell membrane, Multi-pass membrane protein.,Aquaporins,Aquaporin-7, AQP-7, AQP7, Aquaporin7, Aquaporin-7-like, Aquaporin adipose, AQPap, AQP7L
Target Information: Aquaporins/major intrinsic protein (MIP) are a family of water-selective membrane channels. Aquaporin 7 has greater sequence similarity with AQP3 and AQP9 and they may be a subfamily. Aquaporin 7 and AQP3 are at the same chromosomal location suggesting that 9p13 may be a site of an aquaporin cluster. Aquaporin 7 facilitates water, glycerol and urea transport. It may play an important role in sperm function. [provided by RefSeq, Jul 2008]