Description
Product Characteristics:
The product of this gene is a member of the nuclearfactors of activated T cells DNA-binding transcription complex.This complex consists of at least two components: a preexistingcytosolic component that translocates to the nucleus upon T cellreceptor (TCR) stimulation and an inducible nuclear component.Other members of this family of nuclear factors of activated Tcells also participate in the formation of this complex. Theproduct of this gene plays a role in the inducible expression ofcytokine genes in T cells, especially in the induction of the IL-2and IL-4. Alternatively spliced transcript variants encodingdifferent isoforms have been noted for this gene. [provided byRefSeq, Oct 2008].
Subcellular location: Cytoplasm, Nucleus
Synonyms: NFATC4 phospho S168 + S170, p-NFATC4 phospho S168 + S170, NFATC4 cytoplasmic 4, NF ATc4, NF-AT3, NF-ATc4, NFAC4_HUMAN, NFAT3, NFATc4, Nuclear factor of activated T cells cytoplasmic 4, Nuclear factor of activated T cells cytoplasmic calcineurin dependent 4, Nuclear factor of activated T-cells, nuclear factor of activated T-cells cytoplasmic 4, Nuclear factor of activated T-cells cytoplasmic calcineurin-dependent 4, T cell transcription factor NFAT3, T-cell transcription factor NFAT3.
Target Information: The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family of nuclear factors of activated T cells also participate in the formation of this complex. The product of this gene plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of the IL-2 and IL-4. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Oct 2008]