Description
Product Characteristics:
Fibromodulin is a ubiquitous protein that is most prominent in articular cartilage, tendon, and ligament. The human Fibromodulin gene maps to chromosome 1q32 and encodes a 376 amino acid protein.
Subcellular location: Secreted, Extracellular matrix
Synonyms: Collagen binding 59 kDa protein, Collagen-binding 59 kDa protein, Fibromodulin, Fibromodulin precursor, Fibromodulin proteoglycan, FM, FMOD, FMOD_HUMAN, Keratan sulfate proteoglycan fibromodulin, KSPG fibromodulin, SLRR2E.
Target Information: Fibromodulin is a member of a family of small interstitial proteoglycans, containing a central region composed of leucine-rich repeats with 4 keratan sulfate chains flanked by disulfide-bonded terminal domains. It may participate in the assembly of the extracellular matrix as it interacts with type I and type II collagen fibrils and inhibits fibrillogenesis in vitro. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. [provided by RefSeq, Jul 2008]